Calculations of absorbed fractions in small water spheres for low-energy monoenergetic electrons and the Auger-emitting radionuclides(123)Iota and (125)Iota

dc.contributor.authorBousis, C.en
dc.contributor.authorEmfietzoglou, D.en
dc.contributor.authorNikjoo, H.en
dc.date.accessioned2015-11-24T19:32:01Z
dc.date.available2015-11-24T19:32:01Z
dc.identifier.issn1362-3095-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/23351
dc.rightsDefault Licence-
dc.titleCalculations of absorbed fractions in small water spheres for low-energy monoenergetic electrons and the Auger-emitting radionuclides(123)Iota and (125)Iotaen
heal.abstractPurpose: To calculate the absorbed fraction (AF) of low energy electrons in small tissue-equivalent spherical volumes by Monte Carlo (MC) track structure simulation and assess the influence of phase (liquid water versus density-scaled water vapor) and of the continuous-slowing-down approximation (CSDA) used in semi-analytic calculations. Methods: An event-by-event MC code simulating the transport of electrons in both the vapor and liquid phase of water using appropriate electron-water interaction cross sections was used to quantify the energy deposition of low-energy electrons in spherical volumes. Semi-analytic calculations within the CSDA using a convolution integral of the Howell range-energy expressions are also presented for comparison. Results: The AF for spherical volumes of radii from 10-1000 nm are presented for monoenergetic electrons over the energy range 100-10,000 eV and the two Auger-emitting radionuclides (125)I and (123)I. The MC calculated AF for the liquid phase are found to be smaller than those of the (density scaled) gas phase by up to 10-20% for the monoenergetic electrons and 10% for the two Auger-emitters. Differences between the liquid-phase MC results and the semi-analytic CSDA calculations are up to approximately 55% for the monoenergetic electrons and up to approximately 35% for the two Auger-emitters. Conclusions: Condensed-phase effects in the inelastic interaction of low-energy electrons with water have a noticeable but relatively small impact on the AF for the energy range and target sizes examined. Depending on the electron energies, the semi-analytic approach may lead to sizeable errors for target sizes with linear dimensions below 1 micron.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primary10.3109/09553002.2012.666003-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/22348619-
heal.identifier.secondaryhttp://informahealthcare.com/doi/abs/10.3109/09553002.2012.666003-
heal.journalNameInt J Radiat Biolen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2012-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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