Significant improvement of portopulmonary hypertension after 1-week terlipressin treatment
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Authors
Kalambokis, G.
Korantzopoulos, P.
Nikas, S. A.
Theodorou, A.
Tsianos, E. V.
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peer-reviewed
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J Hepatol
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Description
Cirrhosis associated with moderate and severe portopulmonary hypertension carries a poor prognosis. Optimal management has not yet been defined. Current treatment options, such as prostacyclin analogues, endothelin antagonists, and phosphodiesterase-5 inhibitors, are characterized by slow onset of action and various adverse effects, particularly in patients with advanced cirrhosis. Here, we report the significant reduction of pulmonary arterial pressure after 1-week terlipressin treatment in a patient with concomitant hepato-renal syndrome. Terlipressin could be a novel and safe treatment for portopulmonary hypertension.
Description
Keywords
Adult, Antihypertensive Agents/administration & dosage/*therapeutic use, Follow-Up Studies, Humans, Hypertension, Portal/complications/*drug therapy, Hypertension, Pulmonary/complications/*drug therapy, Injections, Intravenous, Lypressin/administration & dosage/*analogs & derivatives/therapeutic use, Male, Shock, Septic, Time Factors
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http://www.ncbi.nlm.nih.gov/pubmed/18280605
http://ac.els-cdn.com/S0168827808000457/1-s2.0-S0168827808000457-main.pdf?_tid=31a3fed2d7b14a78b38318023b5a1302&acdnat=1334041539_5b8706491eb3f1263ba4e87ca07015dd
http://ac.els-cdn.com/S0168827808000457/1-s2.0-S0168827808000457-main.pdf?_tid=31a3fed2d7b14a78b38318023b5a1302&acdnat=1334041539_5b8706491eb3f1263ba4e87ca07015dd
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en
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Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής