Role of the dialyzer membrane on the overall phosphate kinetics during hemodialysis

dc.contributor.authorKatopodis, K. P.en
dc.contributor.authorChala, A.en
dc.contributor.authorKoliousi, E.en
dc.contributor.authorTakouli, L.en
dc.contributor.authorKalaitzidis, R.en
dc.contributor.authorTheodorou, J.en
dc.contributor.authorSiamopoulos, K. C.en
dc.date.accessioned2015-11-24T18:53:08Z
dc.date.available2015-11-24T18:53:08Z
dc.identifier.issn0253-5068-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/18504
dc.rightsDefault Licence-
dc.subjectAcrylic Resinsen
dc.subjectAdulten
dc.subjectAgeden
dc.subjectCellulose/analogs & derivativesen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectKineticsen
dc.subjectMaleen
dc.subject*Membranes, Artificialen
dc.subjectMiddle Ageden
dc.subjectPhosphates/*blood/isolation & purificationen
dc.subjectPolyvinylsen
dc.subjectRenal Dialysis/*instrumentationen
dc.titleRole of the dialyzer membrane on the overall phosphate kinetics during hemodialysisen
heal.abstractBACKGROUND/AIM: We investigated the potential role of the membrane type on phosphate kinetics. METHODS: Six patients on dialysis (HD) were studied using modified cellulose (Hemophan), ethylene-vinyl alcohol (EVAL) and polyacrylonitrile (PAN). Total (TPR), extracellular (EPR) and intracellular (IPR) phosphate removal and effective dialyzer phosphate clearance (K(d)) were determined by the DDQ method. The intercompartment transfer coefficient (K(C)) was calculated using a mathematical model. Erythrocyte phosphate (P(ERY)) and 2,3-biphosphoglycerate (2,3-BPG) concentrations were determined before and after HD. RESULTS: TPR was 1.2+/-0.4, 1.10+/-0.4 and 1.09+/-0.4 g with Hemophan, EVAL and PAN, respectively (p=n.s.). EPR and IPR were independent of membrane type. There was no difference in K(C) between membranes (321+/-70, 338+/-92 and 341+/-83 ml/min, respectively). The P(ERY) and 2,3--BPG remained statistically insignificant for all membranes. CONCLUSION: Our results show that the type of membrane does not influence the kinetics of phosphate during dialysis, neither in the transfer from plasma to dialysate nor from the intra- to the extracellular compartment.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primary10.1159/000087192-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/16088103-
heal.identifier.secondaryhttp://content.karger.com/ProdukteDB/produkte.asp?doi=10.1159/000087192-
heal.journalNameBlood Purifen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2005-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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