The effects of lipid-regulating therapy on haemostatic parameters

dc.contributor.authorMilionis, H. J.en
dc.contributor.authorElisaf, M. S.en
dc.contributor.authorMikhailidis, D. P.en
dc.date.accessioned2015-11-24T19:41:42Z
dc.date.available2015-11-24T19:41:42Z
dc.identifier.issn1381-6128-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/24521
dc.rightsDefault Licence-
dc.subjectArteriosclerosis/drug therapyen
dc.subjectHemostasis/*drug effects/*physiologyen
dc.subjectHumansen
dc.subjectHyperlipidemias/*drug therapyen
dc.subjectHypolipidemic Agents/*therapeutic useen
dc.subjectRheologyen
dc.titleThe effects of lipid-regulating therapy on haemostatic parametersen
heal.abstractThere is growing evidence that the components of the haemostatic system play a significant role in the development and progression of atherosclerosis and its complications. Lipid-lowering interventions have been associated with a significant reduction of morbidity and mortality. However, the improvement in cardiovascular risk seen in several clinical trials is incompletely explained by cholesterol reduction. Therefore, the benefit from lipid lowering drugs may involve non-lipid mechanisms. These include beneficial effects on the arterial wall, improved endothelial function and a favourable influence on blood rheology and thrombogenesis. In this review, we consider the influence of lipid-lowering interventions on rheological and haemostatic parameters as well as the potential clinical relevance of these effects.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/14529557-
heal.journalNameCurr Pharm Desen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2003-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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