Hypertriglyceridaemic waist phenotype criteria and prevalent metabolic triad in women
Φόρτωση...
Ημερομηνία
Συγγραφείς
Gazi, I. F.
Milionis, H. J.
Filippatos, T. D.
Tsimihodimos, V.
Kostapanos, M. S.
Doumas, M.
Tselepis, A. D.
Elisaf, M.
Τίτλος Εφημερίδας
Περιοδικό ISSN
Τίτλος τόμου
Εκδότης
Περίληψη
Τύπος
Είδος δημοσίευσης σε συνέδριο
Είδος περιοδικού
peer reviewed
Είδος εκπαιδευτικού υλικού
Όνομα συνεδρίου
Όνομα περιοδικού
Diabetes-Metabolism Research and Reviews
Όνομα βιβλίου
Σειρά βιβλίου
Έκδοση βιβλίου
Συμπληρωματικός/δευτερεύων τίτλος
Περιγραφή
Background To assess the metabolic profile and the Prevalence of the metabolic triad (i.e. hyperinsulinaemia, hyperapobetalipoproteinaemia, and decreased low-density lipoprotein particle size) in women characterized by the hypertriglyceridaemic waist (HTGW) phenotype and to identify cut-off values for triglycerides and waist circumference, effectively discriminating women with the metabolic triad. Methods Two hundred and twenty-eight female subjects without any history of vascular disease or diabetes mellitus attending an Outpatient Lipid Clinic setting at the University Hospital of Ioannina, Greece were studied. Results Currently available HTGW criteria for women were unable to detect any significant differences in the metabolic profile either in the pre- or postmenopausal women, and proved similar in terms of sensitivity and specificity in identifying women with the metabolic triad. A cut-off value of 1.26 mmol/L for triglycerides and 84.5 cm for waist circumference were determined by Receiver-operating Curve evaluation. Women with both triglycerides and waist circumference above these thresholds had four-fold higher odds of presenting with the metabolic triad compared with women with non-HTGW phenotype. Conclusions AHTGW phenotype definition of 1.26 mmol/L for triglycerides and 84.5 cm for waist circumference may effectively identify Mediterranean women with the atherogenic metabolic triad. Whether these criteria are also associated with a higher incidence of vascular disease and/or new-onset diabetes in women remains to be investigated. Copyright (C) 2007 John Wiley & Sons, Ltd.
Περιγραφή
Λέξεις-κλειδιά
triglycerides, waist circumference, ldl particle size, small dense ldl, metabolic triad, ischemic-heart-disease, dense ldl, cardiovascular risk, follow-up, b levels, cholesterol, men, hyperinsulinemia, predictor, particles
Θεματική κατηγορία
Παραπομπή
Σύνδεσμος
<Go to ISI>://000254075900006
http://onlinelibrary.wiley.com/store/10.1002/dmrr.784/asset/784_ftp.pdf?v=1&t=h0f7wr5b&s=97ae61d4050d9517afc691609652f2d4d238ed3c
http://onlinelibrary.wiley.com/store/10.1002/dmrr.784/asset/784_ftp.pdf?v=1&t=h0f7wr5b&s=97ae61d4050d9517afc691609652f2d4d238ed3c
Γλώσσα
en
Εκδίδον τμήμα/τομέας
Όνομα επιβλέποντος
Εξεταστική επιτροπή
Γενική Περιγραφή / Σχόλια
Ίδρυμα και Σχολή/Τμήμα του υποβάλλοντος
Πανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείας