Primary B-cell gastric lymphomas of mucosa-associated lymphoid tissue. Histological and immunohistochemical study of ten cases on surgical specimens

dc.contributor.authorLavergne, A.en
dc.contributor.authorKanavaros, P.en
dc.contributor.authorGalian, A.en
dc.date.accessioned2015-11-24T18:56:38Z
dc.date.available2015-11-24T18:56:38Z
dc.identifier.issn0213-3911-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/19072
dc.rightsDefault Licence-
dc.subjectAntigens, CD/analysisen
dc.subjectBiopsyen
dc.subjectGastrectomyen
dc.subjectGastric Mucosa/*pathologyen
dc.subjectHumansen
dc.subjectImmunohistochemistryen
dc.subjectLymphoid Tissue/*pathologyen
dc.subjectLymphoma, B-Cell/classification/*pathologyen
dc.subjectNeoplasm Stagingen
dc.subjectTumor Markers, Biologicalen
dc.titlePrimary B-cell gastric lymphomas of mucosa-associated lymphoid tissue. Histological and immunohistochemical study of ten cases on surgical specimensen
heal.abstractTen cases of gastric mucosa-associated lymphoid-tissue B-cell lymphoma were studied on surgical specimens by histology and immunohistochemistry, with monoclonal and polyclonal antibodies for B- and T-cells. For the first time, percentage of centroblast-like cells was appreciated, using their LN1 positivity, by opposition to the negativity of centrocyte-like cells (LN2 immunoreactivity alone). Lymphomas were divided into four main groups: A) centrocyte-like cells; B) centrocyte-like cells and immunocytoma; C) centrocyte-like cells admixed to centroblast-like cells; and D) centrocyte-like cells, immunocytoma and at least 30% of centroblast-like cells. Group C was divided into 3 subgroups: C1 (rare centroblast-like cells); C2 (30-50% of centroblast-like cells); and C3 (predominant centroblast-like cells). Therefore low grade (A, B, C1) and high grade malignancy groups (C2, C3, D) were identified: this preliminary subdivision could be extended in larger series and applied to mucosa-associated lymphoid-tissue lymphoma from other sites. Furthermore, the possible prognostic significance of this subdivision could be evaluated by correlation with long term follow-up.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/1576428-
heal.journalNameHistol Histopatholen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate1992-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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