Fatal meningitis due to Listeria monocytogenes in elderly patients with underlying malignancy
Φόρτωση...
Ημερομηνία
Συγγραφείς
Levidiotou, S.
Charalabopoulos, K.
Vrioni, G.
Chaidos, A.
Polysoidis, K.
Bourantas, K.
Stefanou, D.
Τίτλος Εφημερίδας
Περιοδικό ISSN
Τίτλος τόμου
Εκδότης
Περίληψη
Τύπος
Είδος δημοσίευσης σε συνέδριο
Είδος περιοδικού
peer-reviewed
Είδος εκπαιδευτικού υλικού
Όνομα συνεδρίου
Όνομα περιοδικού
Int J Clin Pract
Όνομα βιβλίου
Σειρά βιβλίου
Έκδοση βιβλίου
Συμπληρωματικός/δευτερεύων τίτλος
Περιγραφή
Adult patients with malignancies are considered to be at a high risk for Listeria monocytogenes meningitis. The Microbiology Laboratory's database of the University Hospital of Ioannina, Greece, was searched for cases of L. monocytogenes during the period from January 1990 to December 2002. Listerial meningitis occurred in three patients: one with brain tumour, one with chronic lymphocytic leukaemia, and one with non-Hodgkin's lymphoma. All the patients were older than 70 and they were actively receiving therapy for their malignancy. L. monocytogenes type 4b was isolated from blood and cerebrospinal fluid. All were treated with ampicillin and gentamicin, but they died shortly after the initiation of the treatment. Experience with the three present cases indicated the high mortality rate due to listerial meningitis in this immunosuppressed population. So, listeriosis should be suspected in patients with meningitis and underlying malignancy. Since meningitis due to L. monocytogenes is not distinguishable clinically from other types of bacterial meningitis, it is recommended to cover Listeria in the initial empirical therapy of bacterial meningitis in immunosuppressed patients.
Περιγραφή
Λέξεις-κλειδιά
Aged, Aged, 80 and over, Brain Neoplasms/complications, Fatal Outcome, Female, Humans, Leukemia, Lymphocytic, Chronic, B-Cell/complications, Lymphoma, Non-Hodgkin/complications, Male, Meningitis, Listeria/*complications, Neoplasms/*complications, Opportunistic Infections/*complications
Θεματική κατηγορία
Παραπομπή
Σύνδεσμος
http://www.ncbi.nlm.nih.gov/pubmed/15117098
http://onlinelibrary.wiley.com/store/10.1111/j.1368-5031.2004.00076.x/asset/j.1368-5031.2004.00076.x.pdf?v=1&t=h0f3gsgm&s=da05390153ad4e752c376559cd141a47160cb34b
http://onlinelibrary.wiley.com/store/10.1111/j.1368-5031.2004.00076.x/asset/j.1368-5031.2004.00076.x.pdf?v=1&t=h0f3gsgm&s=da05390153ad4e752c376559cd141a47160cb34b
Γλώσσα
en
Εκδίδον τμήμα/τομέας
Όνομα επιβλέποντος
Εξεταστική επιτροπή
Γενική Περιγραφή / Σχόλια
Ίδρυμα και Σχολή/Τμήμα του υποβάλλοντος
Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής