Synthesis of the 2,3-epoxide of the 2,3-dimethylbenzo[b]furan, the proposed ultimate mutagen of the benzofuran dioxetanes

dc.contributor.author	Adam, W.	en
dc.contributor.author	Hadjiarapoglou, L.	en
dc.contributor.author	Mosandl, T.	en
dc.contributor.author	Saha-MΞΏller, C.	en
dc.contributor.author	Wild, B.	en
dc.date.accessioned	2015-11-24T16:49:20Z
dc.date.available	2015-11-24T16:49:20Z
dc.identifier.uri	https://olympias.lib.uoi.gr/jspui/handle/123456789/9469
dc.rights	Default Licence	-
dc.title	Synthesis of the 2,3-epoxide of the 2,3-dimethylbenzo[b]furan, the proposed ultimate mutagen of the benzofuran dioxetanes	en
heal.abstract	Dioxetanes can be precursors for mutagenic epoxides"”this provocative hypothesis is the result of this study. Epoxidation of the benzofurans 1 with dimethyldioxirane and deoxygenation of the benzofuran dioxetanes 3 with dimethyl sulfides allows for the first time the synthesis of labile furanepoxides 2. Compounds 2 and 3 are strongly mutagenic in the histidine-auxotrophic Salmonella typhimurium strain TA 100. X = H, Ac.	en
heal.access	campus	-
heal.fullTextAvailability	TRUE	-
heal.identifier.primary	10.1002/anie.199102001	-
heal.identifier.secondary	http://onlinelibrary.wiley.com/doi/10.1002/anie.199102001/abstract	-
heal.journalName	Angewandte Chemie International Edition in English	en
heal.journalType	peer reviewed	-
heal.language	en	-
heal.publicationDate	1991	-
heal.recordProvider	Πανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείας	el
heal.type	journalArticle	-
heal.type.el	Άρθρο Περιοδικού	el
heal.type.en	Journal article	en

Αρχεία

Προβολή: 1 - 1 of 1