Oligoclonal immunoglobulins in serum of patients with chronic viral hepatitis

dc.contributor.authorPapadopoulos, N. M.en
dc.contributor.authorTsianos, E. V.en
dc.contributor.authorCostello, R.en
dc.date.accessioned2015-11-24T19:01:08Z
dc.date.available2015-11-24T19:01:08Z
dc.identifier.issn0887-8013-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/19646
dc.rightsDefault Licence-
dc.subjectDiagnosis, Differentialen
dc.subjectElectrophoresis, Agar Gelen
dc.subjectHepatitis B/diagnosis/*immunologyen
dc.subjectHepatitis C/diagnosis/*immunologyen
dc.subjectHepatitis D/diagnosis/*immunologyen
dc.subjectHepatitis, Chronic/diagnosis/*immunologyen
dc.subjectHepatitis, Viral, Human/*immunologyen
dc.subjectHumansen
dc.subjectImmunoglobulins/*analysisen
dc.subjectOligoclonal Bandsen
dc.titleOligoclonal immunoglobulins in serum of patients with chronic viral hepatitisen
heal.abstractZone electrophoresis on agarose gel was performed in serum samples from patients with chronic viral hepatitis. On the basis of the clinical, serological, and biochemical evaluation, the patients were divided into three categories: chronic type B hepatitis; chronic type delta hepatitis; and chronic non-A-non-B (NANB) hepatitis. The results of the electrophoretic analysis showed a high incidence of oligoclonal immunoglobulin bands (OIBs) in patients with chronic B hepatitis and chronic delta hepatitis and a low incidence of OIBs in patients with NANB. Since other biochemical and serological characteristics are variable and do not correlate with clinical symptoms of disease, we suggest that oligoclonal immunoglobulins could be used as a marker to aid in studies of the natural history and pathologic course of the various types of chronic hepatitis.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/2112595-
heal.identifier.secondaryhttp://onlinelibrary.wiley.com/store/10.1002/jcla.1860040306/asset/1860040306_ftp.pdf?v=1&t=h0owfhfl&s=5fdd6db838fe48b21ed5ebaf0684068967b78e91-
heal.journalNameJ Clin Lab Analen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate1990-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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