Comprendo: Focus and approach
Φόρτωση...
Ημερομηνία
Τίτλος Εφημερίδας
Περιοδικό ISSN
Τίτλος τόμου
Εκδότης
US DEPT HEALTH HUMAN SCIENCES PUBLIC HEALTH SCIENCE
Περίληψη
Τύπος
Είδος δημοσίευσης σε συνέδριο
Είδος περιοδικού
peer reviewed
Είδος εκπαιδευτικού υλικού
Όνομα συνεδρίου
Όνομα περιοδικού
Environ Health Perspect
Όνομα βιβλίου
Σειρά βιβλίου
Έκδοση βιβλίου
Συμπληρωματικός/δευτερεύων τίτλος
Περιγραφή
Tens of thousands of man-made chemicals are in regular use and discharged into the environment. Many of them are known to interfere with the hormonal systems in humans and wildlife. Given the complexity of endocrine systems, there are many ways in which endocrine-disrupting chemicals (EDCs) can affect the body's signaling system, and this makes unraveling the mechanisms of action of these chemicals difficult. A major concern is that some of these EDCs appear to be biologically active at extremely low concentrations. There is growing evidence to indicate that the guiding principle of traditional toxicology that "the dose makes the poison" may not always be the case because some EDCs do not induce the classical dose-response relationships. The European Union project COMPRENDO (Comparative Research on Endocrine Disrupters-Phylogenetic Approach and Common Principles focussing on Androgenic/Antiandrogenic Compounds) therefore aims to develop an understanding of potential health problems posed by androgenic and antiandrogenic compounds (AACs) to wildlife and humans by focusing on the commonalities and differences in responses to AACs across the animal kingdom (from invertebrates to vertebrates).
Περιγραφή
Λέξεις-κλειδιά
androgens, antiandrogens, endocrine disruptor, environmental health, molecular screening, phylogenetic approach, wildlife exposure, aequipecten-irradians lamarck, endocrine disruption, imposex, temperature, gastropoda, exposure, daphnia, gonad
Θεματική κατηγορία
Παραπομπή
Σύνδεσμος
<Go to ISI>://000245475500015
http://ehp03.niehs.nih.gov/article/fetchObjectAttachment.action;jsessionid=57E9AF4E9BDD75D24AF6EA0C2FB4514F?uri=info%3Adoi%2F10.1289%2Fehp.8060&representation=PDF
http://ehp03.niehs.nih.gov/article/fetchObjectAttachment.action;jsessionid=57E9AF4E9BDD75D24AF6EA0C2FB4514F?uri=info%3Adoi%2F10.1289%2Fehp.8060&representation=PDF
Γλώσσα
en
Εκδίδον τμήμα/τομέας
Όνομα επιβλέποντος
Εξεταστική επιτροπή
Γενική Περιγραφή / Σχόλια
Ίδρυμα και Σχολή/Τμήμα του υποβάλλοντος
Πανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείας