Clear cell ovarian carcinoma in a pregnant woman with a history of infertility, endometriosis and unsuccessful IVF treatment

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dc.contributor.authorMakrydimas, G.en
dc.contributor.authorSotiriadis, A.en
dc.contributor.authorParaskevaidis, E.en
dc.contributor.authorPavlidis, N.en
dc.contributor.authorAgnantis, N.en
dc.contributor.authorLolis, D.en
dc.date.accessioned2015-11-24T19:30:26Z
dc.date.available2015-11-24T19:30:26Z
dc.identifier.issn0392-2936-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/23094
dc.rightsDefault Licence-
dc.subjectAdenocarcinoma, Clear Cell/*complications/diagnosisen
dc.subjectAdulten
dc.subjectEndometriosis/*complicationsen
dc.subjectFemaleen
dc.subjectFertilization in Vitroen
dc.subjectHumansen
dc.subjectInfertility, Female/etiology/*therapyen
dc.subjectOvarian Neoplasms/*complications/diagnosisen
dc.subjectPregnancyen
dc.subject*Pregnancy Complications, Neoplastic/diagnosisen
dc.subjectPregnancy Trimester, Firsten
dc.subjectTreatment Failureen
dc.titleClear cell ovarian carcinoma in a pregnant woman with a history of infertility, endometriosis and unsuccessful IVF treatmenten
heal.abstractOvarian cancer in pregnancy is a very rare event. We present here the case of a 37-year-old woman in whom a clear cell ovarian carcinoma was diagnosed in the first trimester of pregnancy. This patient had a history of infertility, endometriosis and two previous unsuccessful attempts of in vitro fertilization. Transvaginal sonography at six gestational weeks revealed a 6 x 4 cm ovarian cyst with an internal papillary excrescence. The cyst persisted throughout the first trimester, whereas the initial CA 125 value of 226 U/ml dropped to 61 U/ml at 12 gestational weeks. Exploratory laparotomy and cystectomy was performed at 14 weeks and the disease was classified as Stage Ic, arising in endometriosis. The couple decided to continue with pregnancy and the woman was followed by serial sonographic, MRI and CA 125 examinations. A cesarean section, hysterectomy, bilateral salpingo-oophorectomy and omentectomy was performed at 34 weeks. Histology and cytology were negative for recurrence. Four months later the woman and baby are doing well. We review cases of ovarian clear cell carcinoma diagnosed during pregnancy and discuss the association of endometriosis, infertility, infertility drugs and ovarian cancer.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/14584666-
heal.journalNameEur J Gynaecol Oncolen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2003-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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