Urinary mineral excretion in preterm neonates during the first month of life
Φόρτωση...
Ημερομηνία
Συγγραφείς
Giapros, V. I.
Papaloukas, A. L.
Andronikou, S. K.
Τίτλος Εφημερίδας
Περιοδικό ISSN
Τίτλος τόμου
Εκδότης
Περίληψη
Τύπος
Είδος δημοσίευσης σε συνέδριο
Είδος περιοδικού
peer-reviewed
Είδος εκπαιδευτικού υλικού
Όνομα συνεδρίου
Όνομα περιοδικού
Neonatology
Όνομα βιβλίου
Σειρά βιβλίου
Έκδοση βιβλίου
Συμπληρωματικός/δευτερεύων τίτλος
Περιγραφή
BACKGROUND: Estimation of urinary parameters in preterm infants is a useful method for identifying metabolic derangements. OBJECTIVES: A prospective, longitudinal, hospital-based study was designed to examine the variability and the associations in renal excretion of calcium (Ca), magnesium (Mg), phosphate (P) and sodium (Na) in formula-fed preterm infants during the first month of life. Patients: Thirty-four infants <32 weeks gestational age, clinically stable, not receiving nephrotoxic drugs. METHODS: Measurements of serum and 8-hour urinary mineral and creatinine (Cr) concentrations were made in all infants during three periods (at 7-10, 14-17 and 21-26 days postnatally). The urinary parameters, FENa, FEP, UCa/UCr, UMg/UCr were calculated. 24- hour urinary excretion was estimated by extrapolation of the 8-hour values. Results: The 24-hour excretion values (median and range) (mmol/kg) during the three study periods were, respectively, for Ca: 0.027 (0.015-0.15), 0.030 (0.007-0.12), 0.031 (0.008-0.12), for P: 0.26 (0.07-0.83), 0.29 (0.06-0.67), 0.41 (0.22-0.70), for Mg: 0.025 (0.007-0.14), 0.025 (0.008-0.16), 0.027 (0.010-0.10) and for Na: 2.85 (0.8-15), 1.45 (0.3-17), 1.56 (0.6-4.3). Na excretion declined while the excretion of the other minerals remained stable. A positive correlation was observed between excretion of Ca, Mg and Na (Ca vs. Na r = 0.63, p < 0.0001; Ca vs. Mg r = 0.65, p < 0.0001; Na vs. Mg r = 0.38, p = 0.012) as well as between the renal parameters FENa, FEP, UCa/UCr, UMg/UCr and the respective 24-hour excretion values (r = 0.80, 0.86, 0.84, 0.81) CONCLUSIONS: Urinary excretion of Ca, P, and Mg in preterm formula-fed infants is stable during the first month of life while urinary Ca, Na and Mg are closely correlated during the same period.
Περιγραφή
Λέξεις-κλειδιά
Calcium/blood/urine, Humans, Infant Formula/*administration & dosage/chemistry, Infant, Newborn, Infant, Premature/blood/*urine, Longitudinal Studies, Magnesium/blood/urine, Minerals/blood/*urine, Phosphorus/blood/urine, Prospective Studies, Sodium/blood/urine, Urinalysis
Θεματική κατηγορία
Παραπομπή
Σύνδεσμος
http://www.ncbi.nlm.nih.gov/pubmed/17377403
http://content.karger.com/ProdukteDB/produkte.asp?doi=10.1159/000097450
http://content.karger.com/ProdukteDB/produkte.asp?doi=10.1159/000097450
Γλώσσα
en
Εκδίδον τμήμα/τομέας
Όνομα επιβλέποντος
Εξεταστική επιτροπή
Γενική Περιγραφή / Σχόλια
Ίδρυμα και Σχολή/Τμήμα του υποβάλλοντος
Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής