Hydroxyindole-O-methyltransferase in Y-79 human retinoblastoma cells: effect of cell attachment
| dc.contributor.author | Kyritsis, A. P. | en |
| dc.contributor.author | Wiechmann, A. F. | en |
| dc.contributor.author | Bok, D. | en |
| dc.contributor.author | Chader, G. J. | en |
| dc.date.accessioned | 2015-11-24T19:12:47Z | |
| dc.date.available | 2015-11-24T19:12:47Z | |
| dc.identifier.issn | 0022-3042 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/21116 | |
| dc.rights | Default Licence | - |
| dc.subject | Acetylserotonin O-Methyltransferase/metabolism | en |
| dc.subject | Animals | en |
| dc.subject | Cattle | en |
| dc.subject | Cell Line | en |
| dc.subject | Cytosol/enzymology | en |
| dc.subject | Eye Neoplasms/*enzymology/pathology | en |
| dc.subject | Fluorescent Antibody Technique | en |
| dc.subject | Humans | en |
| dc.subject | Molecular Weight | en |
| dc.subject | Retina/enzymology/ultrastructure | en |
| dc.subject | Retinoblastoma/*enzymology/pathology | en |
| dc.subject | Staining and Labeling | en |
| dc.title | Hydroxyindole-O-methyltransferase in Y-79 human retinoblastoma cells: effect of cell attachment | en |
| heal.abstract | Hydroxyindole-O-methyltransferase (HIOMT), the enzyme in the final step of melatonin synthesis, is present in the Y-79 human retinoblastoma cell line. Using electroblot immunolabellings, a single band corresponding to HIOMT was observed. Immunofluorescence, sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and quantification of enzyme activity all revealed dramatic increases in HIOMT in cells attached to substrate compared to cells in suspension culture. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/2435851 | - |
| heal.journalName | J Neurochem | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 1987 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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