Role of cytosolic rat liver aldehyde dehydrogenase in the oxidation of acetaldehyde during ethanol metabolism in vivo

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dc.contributor.authorEriksson, C. J.en
dc.contributor.authorMarselos, M.en
dc.contributor.authorKoivula, T.en
dc.date.accessioned2015-11-24T18:53:13Z
dc.date.available2015-11-24T18:53:13Z
dc.identifier.issn0264-6021-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/18520
dc.rightsDefault Licence-
dc.subjectAcetaldehyde/*metabolismen
dc.subjectAldehyde Oxidoreductases/*metabolismen
dc.subjectAnimalsen
dc.subjectCytosol/*enzymologyen
dc.subjectEthanol/*metabolismen
dc.subjectLiver/drug effects/*enzymologyen
dc.subjectMaleen
dc.subjectMitochondria, Liver/enzymologyen
dc.subjectRatsen
dc.subjectRats, Inbred Strainsen
dc.titleRole of cytosolic rat liver aldehyde dehydrogenase in the oxidation of acetaldehyde during ethanol metabolism in vivoen
heal.abstractThe activity of a high-Km aldehyde dehydrogenase in the liver cytosol was increased by phenobarbital induction. No corresponding increase in the oxidation rate of acetaldehyde in vivo was found, and it is concluded that cytosolic aldehyde dehydrogenase plays only a minor role in the oxidation of acetaldehyde during ethanol metabolism.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/1227509-
heal.journalNameBiochem Jen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate1975-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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