Individual renal function in polycystic kidney disease: a follow-up study

dc.contributor.authorFotopoulos, A. D.en
dc.contributor.authorKatopodis, K.en
dc.contributor.authorBalafa, O.en
dc.contributor.authorKatsaraki, A.en
dc.contributor.authorKalaitzidis, R.en
dc.contributor.authorSiamopoulos, K. C.en
dc.date.accessioned2015-11-24T19:10:27Z
dc.date.available2015-11-24T19:10:27Z
dc.identifier.issn0363-9762-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/20830
dc.rightsDefault Licence-
dc.subjectAdolescenten
dc.subjectAdulten
dc.subjectAgeden
dc.subjectAnalysis of Varianceen
dc.subjectFemaleen
dc.subjectFollow-Up Studiesen
dc.subjectGlomerular Filtration Rateen
dc.subjectHumansen
dc.subject*Kidney Function Testsen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectPolycystic Kidney, Autosomal Dominant/*physiopathology/*radionuclide imagingen
dc.subjectRegression Analysisen
dc.subjectSensitivity and Specificityen
dc.subjectTechnetium Tc 99m Dimercaptosuccinic Acid/*diagnostic useen
dc.subjectTechnetium Tc 99m Pentetate/*diagnostic useen
dc.titleIndividual renal function in polycystic kidney disease: a follow-up studyen
heal.abstractPURPOSE: This study was undertaken to determine individual renal function in patients with autosomal dominant polycystic kidney disease (ADPKD). MATERIALS AND METHODS: The authors initially examined (study t1) 25 patients with ADPKD (12 female, 13 male; ages 18 to 68 years). The serum creatinine concentration and glomerular filtration rate, measured by Tc-99m DTPA, were 1.5 +/- 0.56 mg/dl and 65.7 +/- 31 ml.minute-1.1.73 m2, respectively. Thirteen patients had a follow-up study (t2) 2 years after their initial evaluations. Individual renal function was assessed on Tc-99m DMSA renal scans. RESULTS: The mean (+/- SD) difference between left kidney DMSA (DMSA-L) and right kidney DMSA (DMSA-R) was 7.04 % +/- 16.48%. In 20 patients (80%), the left kidney had a lower percentage contribution to the total renal function compared with the right kidney. When the results of the two studies were compared, deterioration in renal function was noted. In the t1 study, the mean serum creatinine concentration and glomerular filtration rate were 1.7 mg/dl and 67.02 ml.minute-1.1.73 m2 respectively, and in the t2 study these values were 2.01 mg/dl and 57.15 ml.minute-1.1.73 m2, respectively. No difference, however, was found in individual renal function in the two studies. CONCLUSIONS: In patients with ADPKD, the percentage contribution of each kidney to total renal function is not equal and remains stable during the progression of renal failure.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/11353299-
heal.journalNameClin Nucl Meden
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2001-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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