Intravenous levosimendan-norepinephrine combination during off-pump coronary artery bypass grafting in a hemodialysis patient with severe myocardial dysfunction

dc.contributor.authorPapadopoulos, G.en
dc.contributor.authorBaikoussis, N. G.en
dc.contributor.authorTzimas, P.en
dc.contributor.authorSiminelakis, S. N.en
dc.contributor.authorKaranikolas, M.en
dc.date.accessioned2015-11-24T19:09:07Z
dc.date.available2015-11-24T19:09:07Z
dc.identifier.issn1749-8090-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/20655
dc.rightsDefault Licence-
dc.subjectAdrenergic alpha-Agonists/*administration & dosageen
dc.subjectCardiotonic Agents/*administration & dosageen
dc.subjectCombined Modality Therapyen
dc.subject*Coronary Artery Bypass, Off-Pumpen
dc.subjectCoronary Stenosis/*drug therapy/etiology/*surgeryen
dc.subjectHumansen
dc.subjectHydrazones/*administration & dosageen
dc.subjectInfusions, Intravenousen
dc.subjectKidney Failure, Chronic/*complications/*therapyen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectNorepinephrine/*administration & dosageen
dc.subjectPyridazines/*administration & dosageen
dc.subject*Renal Dialysisen
dc.titleIntravenous levosimendan-norepinephrine combination during off-pump coronary artery bypass grafting in a hemodialysis patient with severe myocardial dysfunctionen
heal.abstractThis the case of a 63 year-old man with end-stage renal disease (on chronic hemodialysis), unstable angina and significantly impaired myocardial contractility with low left ventricular ejection fraction, who underwent off-pump one vessel coronary bypass surgery. Combined continuous levosimendan and norepinephrine infusion (at 0.07 microg/kg/min and 0.05 microg/kg/min respectively) started immediately after anesthesia induction and continued for 24 hours. The levosimendan/norepinephrine combination helped maintain an appropriate hemodynamic profile, thereby contributing to uneventful completion of surgery and postoperative hemodynamic stability. Although levosimendan is considered contraindicated in ESRD patients, this case report suggests that combined perioperative levosimendan/norepinephrine administration can be useful in carefully selected hemodialysis patients with impaired myocardial contractility and ongoing myocardial ischemia, who undergo off-pump myocardial revascularization surgery.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primary10.1186/1749-8090-5-9-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/20196861-
heal.identifier.secondaryhttp://www.cardiothoracicsurgery.org/content/pdf/1749-8090-5-9.pdf-
heal.journalNameJ Cardiothorac Surgen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2010-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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