Mefloquine-induced eosinophilic pneumonia
| dc.contributor.author | Katsenos, S. | en |
| dc.contributor.author | Psathakis, K. | en |
| dc.contributor.author | Nikolopoulou, M. I. | en |
| dc.contributor.author | Constantopoulos, S. H. | en |
| dc.date.accessioned | 2015-11-24T19:04:59Z | |
| dc.date.available | 2015-11-24T19:04:59Z | |
| dc.identifier.issn | 0277-0008 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/20124 | |
| dc.rights | Default Licence | - |
| dc.subject | Aged | en |
| dc.subject | Antimalarials/*adverse effects/therapeutic use | en |
| dc.subject | Dyspnea/chemically induced | en |
| dc.subject | Female | en |
| dc.subject | Fever/chemically induced | en |
| dc.subject | Humans | en |
| dc.subject | Malaria/prevention & control | en |
| dc.subject | Mefloquine/*adverse effects/therapeutic use | en |
| dc.subject | Physical Exertion | en |
| dc.subject | Pulmonary Eosinophilia/*chemically induced/diagnosis | en |
| dc.subject | Radiography, Thoracic | en |
| dc.subject | South Africa | en |
| dc.title | Mefloquine-induced eosinophilic pneumonia | en |
| heal.abstract | Mefloquine has been widely used for prophylaxis and treatment of patients with chloroquine-resistant malaria; the drug is usually well tolerated. Rarely, adverse effects may be severe, including gastrointestinal disturbances, neuropsychiatric reactions, cardiovascular manifestations, skin lesions, musculoskeletal symptoms, and bone marrow toxicity. We describe a 67-year-old woman with fever, dyspnea on exertion, peripheral blood eosinophilia, and diffuse pulmonary infiltrates on chest radiography. She had taken mefloquine for malaria prophylaxis for an 8-week trip to South Africa. A thorough work-up led to the diagnosis of eosinophilic pneumonia caused by the mefloquine. Her condition improved after the drug was discontinued. To our knowledge, this is the first report of mefloquine-induced eosinophilic pneumonia. Clinicians should be aware of this rare, potential adverse effect of mefloquine. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.primary | 10.1592/phco.27.12.1767 | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/18041895 | - |
| heal.journalName | Pharmacotherapy | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 2007 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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