Transjugular liver biopsy--indications, adequacy, quality of specimens, and complications--a systematic review

dc.contributor.authorKalambokis, G.en
dc.contributor.authorManousou, P.en
dc.contributor.authorVibhakorn, S.en
dc.contributor.authorMarelli, L.en
dc.contributor.authorCholongitas, E.en
dc.contributor.authorSenzolo, M.en
dc.contributor.authorPatch, D.en
dc.contributor.authorBurroughs, A. K.en
dc.date.accessioned2015-11-24T19:10:11Z
dc.date.available2015-11-24T19:10:11Z
dc.identifier.issn0168-8278-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/20798
dc.rightsDefault Licence-
dc.subjectBiopsy, Needle/adverse effects/*methods/standardsen
dc.subjectHumansen
dc.subject*Jugular Veinsen
dc.subjectLiver/*pathologyen
dc.titleTransjugular liver biopsy--indications, adequacy, quality of specimens, and complications--a systematic reviewen
heal.abstractTransjugular liver biopsy (TJLB) is considered an inferior biopsy, used when percutaneous liver biopsy (PLB) is contraindicated. According to recent literature, specimens with 6 complete portal tracts (CPTs) are needed for histological diagnosis of chronic liver disease but 11 CPTs to reliably stage and grade. Mean CPT number in PLB series is 7.5; more passes increase complications. Sixty-four series reporting 7649 TJLBs were evaluated for quality of specimen and safety. Major indications were coagulation disorders and/or ascites. Success rate was 96.8%. Fragmentation rate was 34.3%, not correlating with length or diagnostic adequacy. With a mean of 2.7 passes, mean CPT number was 6.8. Histological diagnosis was achieved in 96.1% of TJLBs, correlating with length (p=0.007) and CPT number (p=0.04). Tru-Cut specimens had a mean CPT number of 7.5 and, compared to Menghini specimens, were longer (p<0.008), less fragmented (p<0.001) and more diagnostic (p<0.001). Thinner needles (>16-G) provided significantly longer and less fragmented specimens. Minor and major complication rates were 6.5% and 0.56%, respectively, and increased in children, but not with additional passes. In adults, mortality was 0.09% (haemorrhage 0.06%; ventricular arrhythmia 0.03%). TJLB is safe, providing specimens qualitatively comparable to PLB, and may improve further using > or = 18-G Tru-Cut needle and >3 passes.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primary10.1016/j.jhep.2007.05.001-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/17561303-
heal.identifier.secondaryhttp://ac.els-cdn.com/S0168827807002838/1-s2.0-S0168827807002838-main.pdf?_tid=acdb919857cbf3cad4438cff02e1aba5&acdnat=1334041551_898afab448301f78de013bb93d01fafe-
heal.journalNameJ Hepatolen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2007-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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