Photocatalytic degradation study of diclofenac over aqueous TiO2 suspensions
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Ημερομηνία
Τίτλος Εφημερίδας
Περιοδικό ISSN
Τίτλος τόμου
Εκδότης
Elsevier
Περίληψη
Τύπος
Είδος δημοσίευσης σε συνέδριο
Είδος περιοδικού
peer reviewed
Είδος εκπαιδευτικού υλικού
Όνομα συνεδρίου
Όνομα περιοδικού
Applied Catalysis B-Environmental
Όνομα βιβλίου
Σειρά βιβλίου
Έκδοση βιβλίου
Συμπληρωματικός/δευτερεύων τίτλος
Περιγραφή
Diclofenac (2-[2,6'-(dichlorophenyl)amino]phenylacetic acid) is a non-steroidal anti-inflammatory drug used to treat inflammatory and painful diseases of rheumatic and non-rheumatic origin. The present work deals with the photocatalytic transformation of diclofenac, under simulated solar irradiation using titania suspensions as catalyst, to assess the decomposition of the pharmaceutical compound, to identify intermediates, as well as to elucidate some mechanistic details of the degradation. The variation of TiO2 amount and initial diclofenac concentration on the reaction rate, were systematically investigated. The use of the response surface methodology allowed to fit the optimal values of the parameters leading to the degradation of the pollutant. Also, a single polynomial expression modeling the reaction was obtained. Photomineralization of the substrate in terms of chlorine ions release was rather a quick process (within 1 h), while the amino moiety is mainly transformed into NH4+ and in a lesser extend into NO3- ions. Evolution of CO2 (loss of TOC) was found to occur within 2 h of irradiation. LC/MS was brought to bear in assessing the temporal course of the photocatalyzed process. Based on our findings a tentative degradation pathway is proposed for the photocatalytic degradation of diclofenac based on the formation of hydroxy-derivatives before the complete mineralization of the starting molecule. In addition Microtox bioassay (Vibrio fischeri) was employed in evaluating the ecotoxicity of solutions treated by photocatalysis. Results clearly demonstrate the efficiency of the photocatalytic process in the detoxification of the irradiated solution. (c) 2006 Elsevier B.V. All rights reserved.
Περιγραφή
Λέξεις-κλειδιά
photocatalysis, tio2, experimental design, mineralization, toxicity, diclofenac, pharmaceutical drug diclofenac, surface waters, advanced oxidation, natural-waters, clofibric acid, ibuprofen, fate, photodegradation, identification, toxicity
Θεματική κατηγορία
Παραπομπή
Σύνδεσμος
<Go to ISI>://000240893800006
http://ac.els-cdn.com/S0926337306001299/1-s2.0-S0926337306001299-main.pdf?_tid=ba4040609ac98a22cad041ca80a9d361&acdnat=1333022780_9027e3ad06661c296cc312c59d6cdc5a
http://ac.els-cdn.com/S0926337306001299/1-s2.0-S0926337306001299-main.pdf?_tid=ba4040609ac98a22cad041ca80a9d361&acdnat=1333022780_9027e3ad06661c296cc312c59d6cdc5a
Γλώσσα
en
Εκδίδον τμήμα/τομέας
Όνομα επιβλέποντος
Εξεταστική επιτροπή
Γενική Περιγραφή / Σχόλια
Ίδρυμα και Σχολή/Τμήμα του υποβάλλοντος
Πανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείας