A predictive model of short cervix at 20-24 weeks using first-trimester cervical length measurement and maternal history

dc.contributor.authorSouka, A. P.en
dc.contributor.authorPapastefanou, I.en
dc.contributor.authorMichalitsi, V.en
dc.contributor.authorPapadopoulos, G. K.en
dc.contributor.authorKassanos, D.en
dc.date.accessioned2015-11-24T19:39:43Z
dc.date.available2015-11-24T19:39:43Z
dc.identifier.issn1097-0223-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/24269
dc.rightsDefault Licence-
dc.subjectAdolescenten
dc.subjectAdulten
dc.subject*Cervical Length Measurementen
dc.subjectCervix Uteri/*ultrasonographyen
dc.subjectFeasibility Studiesen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectMiddle Ageden
dc.subjectModels, Biologicalen
dc.subjectPregnancyen
dc.subjectPregnancy Complications/*ultrasonographyen
dc.subjectPregnancy Trimester, Firsten
dc.subjectProspective Studiesen
dc.subjectUterine Cervical Diseases/*ultrasonographyen
dc.subjectYoung Adulten
dc.titleA predictive model of short cervix at 20-24 weeks using first-trimester cervical length measurement and maternal historyen
heal.abstractOBJECTIVES: To develop a model for the prediction of short cervix ( </= 15 mm) at 20-24 weeks by combining maternal history and transvaginal ultrasonographic measurement of cervical length at 11-14 weeks. To explore the value of an additional ultrasound examination of the cervix at about 17 weeks. METHODS: Longitudinal prospective study in 800 unselected pregnant women presenting for first-trimester ultrasound assessment by nuchal translucency and serum biochemistry. Cervical length was evaluated transvaginally between 11 weeks and 13 weeks and 6 days (cx1), at 16-19 weeks (cx2) and 20-24 weeks (cx3). Backward multiple logistic regression analysis with cx3 </= 15 mm as the dependent variable was used to identify the predictors of a short cervix at 20-24 weeks. RESULTS: Cx1 and history of preterm delivery were significant independent contributors of a short cervix at 20-24 weeks [area under the curve (AUC 0.808, p < 0.001, Model) 1]. Furthermore, the cx1/cx2 ratio was a significant independent predictor of a short cervix at 20-24 weeks (odds ratio = 58.325 p = 0.012). The addition of the cx1/cx2 ratio improved the model (AUC = 0.878, p < 0.001, Model 2). CONCLUSIONS: A short cervix at 20-24 weeks can be predicted at the 11-14 weeks scan. The addition of a cervical measurement at about 17 weeks can improve the prediction model.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primary10.1002/pd.2683-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/21268041-
heal.identifier.secondaryhttp://onlinelibrary.wiley.com/store/10.1002/pd.2683/asset/2683_ftp.pdf?v=1&t=h0utqihy&s=b58b32824669ce7c7811b50c7bbfa915885e122c-
heal.journalNamePrenat Diagnen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2011-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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