An electron microscopic and biochemical study of the effects of glucagon on newborn rat hepatocytes

dc.contributor.authorKotoulas, O. B.en
dc.date.accessioned2015-11-24T19:36:38Z
dc.date.available2015-11-24T19:36:38Z
dc.identifier.issn0376-6160-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/23914
dc.rightsDefault Licence-
dc.subjectAnimalsen
dc.subjectAnimals, Newbornen
dc.subjectGlucagon/*pharmacologyen
dc.subjectGlucosidases/*metabolismen
dc.subjectLiver/*drug effects/enzymology/ultrastructureen
dc.subjectLiver Glycogen/metabolismen
dc.subjectLysosomes/metabolismen
dc.subjectMicroscopy, Electronen
dc.subjectRatsen
dc.subjectRats, Inbred Strainsen
dc.subjectalpha-Glucosidases/*metabolismen
dc.titleAn electron microscopic and biochemical study of the effects of glucagon on newborn rat hepatocytesen
heal.abstractCertain effects of glucagon administration on newborn rat hepatocytes were studied using biochemical assays, electron microscopy and quantitative morphometry. Glucagon accelerated the normal postnatal hyaloplasmic glycogen breakdown and the lysosomal glycogen breakdown. The glucagon-treated animals showed an increased activity of the enzyme, acid a 1,4 glucosidase (maltase). The results suggest that the catabolism of lysosomal glycogen is controlled by those agents that regulate the catabolism of hyaloplasmic glycogen and that this control is mediated through changes in the activity of the lysosomal acid a 1,4 glucosidases.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/6399004-
heal.journalNameBull Assoc Anat (Nancy)en
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate1984-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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