Association of liver cirrhosis related IgA nephropathy with portal hypertension

dc.contributor.authorKalambokis, G.en
dc.contributor.authorChristou, L.en
dc.contributor.authorStefanou, D.en
dc.contributor.authorArkoumani, E.en
dc.contributor.authorTsianos, E. V.en
dc.date.accessioned2015-11-24T19:34:48Z
dc.date.available2015-11-24T19:34:48Z
dc.identifier.issn1007-9327-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/23653
dc.rightsDefault Licence-
dc.subjectAdulten
dc.subjectGlomerulonephritis, IGA/diagnosis/*etiologyen
dc.subjectHumansen
dc.subjectHypertension, Portal/*complications/diagnosisen
dc.subjectKidneyen
dc.subjectLiver Cirrhosis/*complicationsen
dc.subjectMaleen
dc.subjectSplenic Vein/pathologyen
dc.subjectVenous Thrombosis/complications/diagnosisen
dc.titleAssociation of liver cirrhosis related IgA nephropathy with portal hypertensionen
heal.abstractA high incidence of IgA nephropathy has been reported in patients with liver cirrhosis, though, clinically evident nephrotic syndrome is very uncommon. Impaired hepatic clearance of circulating IgA immune complexes and subsequent deposition in renal glomeruli has been considered principally in the pathogenesis of liver cirrhosis associated IgA nephropathy. Here we report on a patient with cryptogenic liver cirrhosis and splenic vein thrombosis, who presented with nephrotic syndrome. Renal biopsy showed findings consistent with IgA nephropathy. Lower endoscopy showed features of portal hypertensive colopathy. Following initiation of propranolol and anticoagulant treatment to reduce portal pressure, a gradual decrease of proteinuria and hematuria to normal range was noted. The potential pathogenetic role of portal hypertension in the development of IgA nephropathy in cirrhotic patients is discussed.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/17963311-
heal.journalNameWorld J Gastroenterolen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2007-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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