The diagnostic value and safety of transbronchial needle aspiration biopsy in children with mediastinal lymphadenopathy
Φόρτωση...
Ημερομηνία
Συγγραφείς
Goussard, P.
Gie, R. P.
Kling, S.
Nel, E. D.
Louw, M.
Schubert, P. T.
Rhode, D.
Vanker, A.
Andronikou, S.
Τίτλος Εφημερίδας
Περιοδικό ISSN
Τίτλος τόμου
Εκδότης
Περίληψη
Τύπος
Είδος δημοσίευσης σε συνέδριο
Είδος περιοδικού
peer-reviewed
Είδος εκπαιδευτικού υλικού
Όνομα συνεδρίου
Όνομα περιοδικού
Pediatr Pulmonol
Όνομα βιβλίου
Σειρά βιβλίου
Έκδοση βιβλίου
Συμπληρωματικός/δευτερεύων τίτλος
Περιγραφή
INTRODUCTION: Anterior mediastinal masses in children can have different causes which includes, Mycobacterium tuberculosis (MTB) or malignant lymphadenopathy. Transbronchial needle aspiration (TBNA) has been described as a safe and effective diagnostic procedure in adult patients with lung cancer. AIM: To describe the use of TBNA as a diagnostic test in children with large subcarinal lymphadenopathy and to determine the safety of the procedure in children. PATIENTS AND METHODS: Prospective descriptive study of children with subcarinal mediastinal lymph nodes who underwent TBNA. The majority of the children were referred due to treatment failure. Children were enrolled if the diagnosis remained unclear after computer tomography of the chest. RESULTS: Thirty patients were enrolled in this study; TBNA was done in 28 patients. A definitive diagnosis was made by TBNA in 54% (n = 15) of patients; MTB lymphadenopathy (n = 13), metastatic nephroblastoma (n = 1), and fibrosing mediastinitis (n = 1). In seven (25%) cases the TBNA was the sole source of the specimens from which the definitive diagnosis was made. No serious complications were encountered during or after the procedure. CONCLUSION: TBNA is a safe procedure in children with mediastinal lymphadenopathy of unknown cause resulting in a definitive diagnosis in 57% of cases. TBNA adds additional value to flexible bronchoscopy in the diagnosis of mediastinal lymphadenopathy in children.
Περιγραφή
Λέξεις-κλειδιά
Adolescent, *Biopsy, Needle, Bronchoscopy, Child, Child, Preschool, Female, Fibrosis/diagnosis, Humans, Infant, Lymph Nodes/*pathology, Lymphatic Diseases/*diagnosis, Male, Mediastinal Diseases/*diagnosis, Mediastinal Neoplasms/diagnosis/secondary, Mediastinitis/diagnosis, Mediastinum/pathology, Mycobacterium tuberculosis/isolation & purification, Prospective Studies, Radiography, Thoracic, Tuberculosis/diagnosis, Wilms Tumor/diagnosis/secondary
Θεματική κατηγορία
Παραπομπή
Σύνδεσμος
http://www.ncbi.nlm.nih.gov/pubmed/20717911
http://onlinelibrary.wiley.com/store/10.1002/ppul.21303/asset/21303_ftp.pdf?v=1&t=h0cayg0g&s=de0fd29e9c246ecc736dc33476140e1cb437e9b4
http://onlinelibrary.wiley.com/store/10.1002/ppul.21303/asset/21303_ftp.pdf?v=1&t=h0cayg0g&s=de0fd29e9c246ecc736dc33476140e1cb437e9b4
Γλώσσα
en
Εκδίδον τμήμα/τομέας
Όνομα επιβλέποντος
Εξεταστική επιτροπή
Γενική Περιγραφή / Σχόλια
Ίδρυμα και Σχολή/Τμήμα του υποβάλλοντος
Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής