Serum estimation of carcinoembryonic antigen, beta(2)-microglobulin and calcitonin as tumor markers in primary lung cancer
| dc.contributor.author | Charalabopoulos, K. | en |
| dc.contributor.author | Papalimneou, V. | en |
| dc.contributor.author | Charalabopoulos, A. | en |
| dc.contributor.author | Zoganas, L. | en |
| dc.contributor.author | Andronadi, V. | en |
| dc.contributor.author | Stefanou, D. | en |
| dc.contributor.author | Agnantis, N. J. | en |
| dc.date.accessioned | 2015-11-24T18:52:11Z | |
| dc.date.available | 2015-11-24T18:52:11Z | |
| dc.identifier.issn | 1107-0625 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/18367 | |
| dc.rights | Default Licence | - |
| dc.title | Serum estimation of carcinoembryonic antigen, beta(2)-microglobulin and calcitonin as tumor markers in primary lung cancer | en |
| heal.abstract | PURPOSE: The aim of this study was to estimate the diagnostic significance of carcinoembryonic antigen (CEA), beta(2)-microglobulin (beta(2)-MG), and calcitonin (CAL) as tumor markers in patients with lung cancer. PATIENTS AND METHODS: Sixty patients were included and CEA, beta(2)-MG, and CAL serum levels were measured before treatment, and one and 6 months after treatment. RESULTS: The results taken showed that CEA mean baseline level was 23.4 ng/ml (normal range 0-5 ng/ml and up to 8 ng/ml in smokers), elevated in 80% of small-cell lung cancer (SCLC) cases, in 93% of adenocarcinomas, in 84% of squamous-cell carcinomas, and in 84% of large-cell carcinomas. The mean beta(2)-MG level was 3.6 mg/l (normal range 0.7-3.4 mg/l), elevated in 70% of SCLC, in 40% of adenocarcinomas, in 66% of large-cell and in 50% of squamouscell carcinomas. The mean CAL level was 170 pg/ml (normal < 26 pg/ml), elevated in 60% of SCLC, in 33% of adenocarcinomas, in 16% of large-cell and in 16% of squamouscell carcinomas. CONCLUSION: CEA, beta(2)-MG, and CAL can be used as tumor markers with diagnostic value in primary lung cancer. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/17415866 | - |
| heal.journalName | J BUON | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 2003 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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