Follow-up of albumin excretion during pregnancy and post partum in type 1 diabetic patients in comparison with health pregnant probands

Απλή σελίδα τεκμηρίου
dc.contributor.authorDiglas, J.en
dc.contributor.authorBali, C.en
dc.contributor.authorSimon, C.en
dc.contributor.authorStrassegger-Bohm, D.en
dc.contributor.authorIrsigler, K.en
dc.date.accessioned2015-11-24T19:15:29Z
dc.date.available2015-11-24T19:15:29Z
dc.identifier.issn0303-8173-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/21524
dc.rightsDefault Licence-
dc.subjectAdulten
dc.subjectAlbuminuria/diagnosisen
dc.subjectCreatinine/urineen
dc.subjectDiabetes Mellitus, Type 1/diagnosisen
dc.subjectDiabetic Nephropathies/diagnosisen
dc.subjectFemaleen
dc.subjectFollow-Up Studiesen
dc.subjectGestational Ageen
dc.subjectHumansen
dc.subjectInfant, Newbornen
dc.subjectKidney Function Testsen
dc.subjectPregnancyen
dc.subjectPregnancy Complications/diagnosisen
dc.subjectPregnancy in Diabetics/diagnosisen
dc.subjectPuerperal Disorders/diagnosisen
dc.subjectReference Valuesen
dc.titleFollow-up of albumin excretion during pregnancy and post partum in type 1 diabetic patients in comparison with health pregnant probandsen
heal.abstract32 diabetic and 31 metabolic healthy pregnant women are studied to answer the following questions: Is there a difference in the albumin-excretion rate (AER) during the pregnancy in primary normoalbuminuric type 1 diabetics and non-diabetics? Is there a difference 6 months post partum between the 2 groups? The average age of the diabetics (D) is 28, of the non-diabetics (ND) 27 years; the diabetics suffer from diabetes mellitus 12.5 years. In the 16th week of pregnancy, we find a AER (D vs. ND) of 5.0 vs. 2.37 micrograms/min (not significant [n.s.]), creatinin in serum 0.77 vs. 0.75 mg/dl (p < 0.05), creatinin clearance 92.5 vs. 103.4 ml/min (n.s.). In the 28th and in the 34th to 38th week, there is no significant elevation of the AER compared to the 16th week; but there is a significant elevation in the diabetics vs. the non-diabetics. 6 months post partum, the AER (D vs. ND) are: 6.13 vs. 5.11 micrograms/min (n.s. vs. 16th week and D vs. ND); in each group one person is found with a positive microalbuminuria (MA): 48.2 micrograms/min (D) and 27.4 mg/min (ND). Another diabetic woman shows post partum an isolated higher value of creatinin in serum: 1.5 mg/dl (without MA). This parameter is post partum significant higher (0.97 [D], 0.96 [ND] mg/dl) than in the 16th week of pregnancy (0.77 [D], 0.75 [ND] mg/dl). The creatinin clearance decreases post partum (pp): 92.2 ml/min (pp) vs. 102.0 ml/min (28th week) in the diabetics (n.s.) and 80.6 ml/min (pp) vs. 111.0 ml/min (28th week) in the non-diabetics (p < 0.05). Concerning the studied renal parameters, there is a significant difference of the albumin-excretion rates during the pregnancy between preconceptional normoalbuminuric type 1 diabetic and non-diabetic women, but 6 months post partum, there is no significant difference. The diabetics show a significant increase of the creatinin in urine and in serum and no significant change of the creatinin clearance 6 months post partum.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/9480617-
heal.journalNameActa Med Austriacaen
heal.journalTypepeer-reviewed-
heal.languagede-
heal.publicationDate1997-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

Αρχεία

Φάκελος/Πακέτο αδειών

Προβολή: 1 - 1 of 1
Μικρογραφία εικόνας
Ονομα:
license.txt
Μέγεθος:
1.74 KB
Μορφότυπο:
Item-specific license agreed upon to submission
Περιγραφή:
Κατεβάστε

Συλλογές

Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ