Synthesis of 1-aroylmethylpyrroles as useful intermediates for further chemical transformation
dc.contributor.author | Karousis, N. | en |
dc.contributor.author | Koriatopoulou, K. | en |
dc.contributor.author | Varvounis, G. | en |
dc.date.accessioned | 2015-11-24T16:49:11Z | |
dc.date.available | 2015-11-24T16:49:11Z | |
dc.identifier.issn | 1424-6376 | - |
dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/9443 | |
dc.rights | Default Licence | - |
dc.subject | pyrroles | en |
dc.subject | 1-aroylmethylpyrroles | en |
dc.subject | alkylation | en |
dc.subject | reduction | en |
dc.subject | antipsychotic agents | en |
dc.subject | convenient synthesis | en |
dc.subject | pyrrole chemistry | en |
dc.subject | lukianol | en |
dc.subject | facile | en |
dc.title | Synthesis of 1-aroylmethylpyrroles as useful intermediates for further chemical transformation | en |
heal.abstract | The synthesis of 1-aroylmethylpyrroles from 2-bromo-1-(2-aminophenyl)ethan-1-one and mono-di- or tri-substituted 1H-pyrroles, has been investigated. The reactions take place at r.t. or 80 degrees C in DMF containing potassium carbonate. Reduction of 1-[2-(2-aminophenyl)-2-oxoethyl]-4-bromo-1H-pyrrole-2-carbaldehyde with sodium borohydride gave racemic 1-(2-aminophenyl)-2-[4-bromo-2-(hydroxymethyl)-1H-pyrrol-1-yl]ethanol. | en |
heal.access | campus | - |
heal.fullTextAvailability | TRUE | - |
heal.identifier.secondary | <Go to ISI>://000254896500014 | - |
heal.journalName | Arkivoc | en |
heal.journalType | peer reviewed | - |
heal.language | en | - |
heal.publicationDate | 2008 | - |
heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείας | el |
heal.type | journalArticle | - |
heal.type.el | Άρθρο Περιοδικού | el |
heal.type.en | Journal article | en |
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