Synthesis of 1-aroylmethylpyrroles as useful intermediates for further chemical transformation

dc.contributor.authorKarousis, N.en
dc.contributor.authorKoriatopoulou, K.en
dc.contributor.authorVarvounis, G.en
dc.date.accessioned2015-11-24T16:49:11Z
dc.date.available2015-11-24T16:49:11Z
dc.identifier.issn1424-6376-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/9443
dc.rightsDefault Licence-
dc.subjectpyrrolesen
dc.subject1-aroylmethylpyrrolesen
dc.subjectalkylationen
dc.subjectreductionen
dc.subjectantipsychotic agentsen
dc.subjectconvenient synthesisen
dc.subjectpyrrole chemistryen
dc.subjectlukianolen
dc.subjectfacileen
dc.titleSynthesis of 1-aroylmethylpyrroles as useful intermediates for further chemical transformationen
heal.abstractThe synthesis of 1-aroylmethylpyrroles from 2-bromo-1-(2-aminophenyl)ethan-1-one and mono-di- or tri-substituted 1H-pyrroles, has been investigated. The reactions take place at r.t. or 80 degrees C in DMF containing potassium carbonate. Reduction of 1-[2-(2-aminophenyl)-2-oxoethyl]-4-bromo-1H-pyrrole-2-carbaldehyde with sodium borohydride gave racemic 1-(2-aminophenyl)-2-[4-bromo-2-(hydroxymethyl)-1H-pyrrol-1-yl]ethanol.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondary<Go to ISI>://000254896500014-
heal.journalNameArkivocen
heal.journalTypepeer reviewed-
heal.languageen-
heal.publicationDate2008-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείαςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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