Immune thrombocytopenia attributed to brucellosis and other mechanisms of Brucella-induced thrombocytopenia

dc.contributor.authorPappas, G.en
dc.contributor.authorKitsanou, M.en
dc.contributor.authorChristou, L.en
dc.contributor.authorTsianos, E.en
dc.date.accessioned2015-11-24T19:12:05Z
dc.date.available2015-11-24T19:12:05Z
dc.identifier.issn0361-8609-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/21014
dc.rightsDefault Licence-
dc.subjectAcute Diseaseen
dc.subjectAdrenal Cortex Hormones/therapeutic useen
dc.subjectAgeden
dc.subjectAged, 80 and overen
dc.subjectAnti-Bacterial Agents/therapeutic useen
dc.subjectBrucellaen
dc.subjectBrucellosis/blood/*complications/drug therapyen
dc.subjectCoombs' Testen
dc.subjectDoxycycline/therapeutic useen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectPlatelet Counten
dc.subjectPurpura, Thrombocytopenic, Idiopathic/blood/drug therapy/*microbiologyen
dc.subjectStreptomycin/therapeutic useen
dc.titleImmune thrombocytopenia attributed to brucellosis and other mechanisms of Brucella-induced thrombocytopeniaen
heal.abstractThrombocytopenia often complicates the course of acute brucellosis, mainly due to bone marrow suppression or hypersplenism. Immune thrombocytopenia is also reported in brucellosis, resulting usually in massive thrombocytopenia, purpura, and spontaneous hemorrhage. We describe a case of acute brucellosis in an 85-year old woman, who presented with fever, purpuric skin lesions, anemia, and rhinorrhagia. The absolute platelet count was 1000/microL. Direct and indirect Coombs tests were positive, and a cold-agglutinin was detected. The patient was diagnosed as suffering from brucellosis on the basis of a strongly positive serologic reaction and was treated with doxycycline, streptomycin, and a short course of corticosteroids, with a rapid rise in platelet number.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primary10.1002/ajh.10473-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/14978693-
heal.identifier.secondaryhttp://onlinelibrary.wiley.com/store/10.1002/ajh.10473/asset/10473_ftp.pdf?v=1&t=h0p16w8m&s=5a65ca1867c3956e1e3b0dbe0c27b73260af12de-
heal.journalNameAm J Hematolen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2004-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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