Spectrum and frequency of ophthalmologic manifestations in patients with inflammatory bowel disease: a prospective single-center study
Φόρτωση...
Ημερομηνία
Συγγραφείς
Felekis, T.
Katsanos, K.
Kitsanou, M.
Trakos, N.
Theopistos, V.
Christodoulou, D.
Asproudis, I.
Tsianos, E. V.
Τίτλος Εφημερίδας
Περιοδικό ISSN
Τίτλος τόμου
Εκδότης
Περίληψη
Τύπος
Είδος δημοσίευσης σε συνέδριο
Είδος περιοδικού
peer-reviewed
Είδος εκπαιδευτικού υλικού
Όνομα συνεδρίου
Όνομα περιοδικού
Inflamm Bowel Dis
Όνομα βιβλίου
Σειρά βιβλίου
Έκδοση βιβλίου
Συμπληρωματικός/δευτερεύων τίτλος
Περιγραφή
BACKGROUND: The frequency and spectrum of ophthalmologic manifestations in patients with inflammatory bowel disease (IBD) has been reported to vary among studies; however, rare and silent manifestations have not been extensively studied. METHODS: This was a prospective study of 60 patients diagnosed with IBD who underwent full ophthalmologic examination, including visual acuity, slit lamp examination of the anterior segments, intraocular pressure, and fundus examination accompanied by color photography. Thirty-seven (61,7%) patients were diagnosed with ulcerative colitis (UC) and 23 (38,3%) with Crohn's disease (CD). Data from 276 control individuals were used for the determination of the prevalence of dry eye in our area. RESULTS: Ophthalmologic manifestations were diagnosed in 26 (43%) patients (14 UC, 12 CD; 12 males and 14 females). Conjunctivitis was diagnosed in 1 patient (CD), episcleritis in 2 patients (UC), and iridocyclitis in 3 (CD). Fundus examination showed 1 patient (CD) with unilateral choroiditis, 1 (UC) with retinal vasculitis, and 1 (CD) with optic neuritis. Retinal pigment epithelium disturbances (RPED) were present in 3 patients (1 CD, 2 UC) and 2 had serous retinal detachment. In total, 13/60 patients (22%) had dry eye compared with the 11% prevalence in controls. Eight patients developed glucocorticosteroid-induced cataracts, 2 of them treated surgically. CONCLUSIONS: This study demonstrated the prevalence of the spectrum of ophthalmologic manifestations in the IBD population, including some rare and silent findings that may merit consideration and early intervention.
Περιγραφή
Λέξεις-κλειδιά
Adolescent, Adult, Aged, Aged, 80 and over, Case-Control Studies, Colitis, Ulcerative/*complications/diagnosis/drug therapy, Crohn Disease/*complications/diagnosis/drug therapy, Eye Diseases/diagnosis/*etiology, Female, Humans, Incidence, Male, Middle Aged, Prevalence, Prognosis, Prospective Studies, Steroids/adverse effects, Young Adult
Θεματική κατηγορία
Παραπομπή
Σύνδεσμος
http://www.ncbi.nlm.nih.gov/pubmed/18626979
http://onlinelibrary.wiley.com/store/10.1002/ibd.20584/asset/20584_ftp.pdf?v=1&t=h05ido5n&s=e19694881aa8f09ea251bf875701b070fcee965d
http://onlinelibrary.wiley.com/store/10.1002/ibd.20584/asset/20584_ftp.pdf?v=1&t=h05ido5n&s=e19694881aa8f09ea251bf875701b070fcee965d
Γλώσσα
en
Εκδίδον τμήμα/τομέας
Όνομα επιβλέποντος
Εξεταστική επιτροπή
Γενική Περιγραφή / Σχόλια
Ίδρυμα και Σχολή/Τμήμα του υποβάλλοντος
Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής