Spectrum and frequency of ophthalmologic manifestations in patients with inflammatory bowel disease: a prospective single-center study

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dc.contributor.authorFelekis, T.en
dc.contributor.authorKatsanos, K.en
dc.contributor.authorKitsanou, M.en
dc.contributor.authorTrakos, N.en
dc.contributor.authorTheopistos, V.en
dc.contributor.authorChristodoulou, D.en
dc.contributor.authorAsproudis, I.en
dc.contributor.authorTsianos, E. V.en
dc.date.accessioned2015-11-24T18:50:54Z
dc.date.available2015-11-24T18:50:54Z
dc.identifier.issn1536-4844-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/18172
dc.rightsDefault Licence-
dc.subjectAdolescenten
dc.subjectAdulten
dc.subjectAgeden
dc.subjectAged, 80 and overen
dc.subjectCase-Control Studiesen
dc.subjectColitis, Ulcerative/*complications/diagnosis/drug therapyen
dc.subjectCrohn Disease/*complications/diagnosis/drug therapyen
dc.subjectEye Diseases/diagnosis/*etiologyen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectIncidenceen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectPrevalenceen
dc.subjectPrognosisen
dc.subjectProspective Studiesen
dc.subjectSteroids/adverse effectsen
dc.subjectYoung Adulten
dc.titleSpectrum and frequency of ophthalmologic manifestations in patients with inflammatory bowel disease: a prospective single-center studyen
heal.abstractBACKGROUND: The frequency and spectrum of ophthalmologic manifestations in patients with inflammatory bowel disease (IBD) has been reported to vary among studies; however, rare and silent manifestations have not been extensively studied. METHODS: This was a prospective study of 60 patients diagnosed with IBD who underwent full ophthalmologic examination, including visual acuity, slit lamp examination of the anterior segments, intraocular pressure, and fundus examination accompanied by color photography. Thirty-seven (61,7%) patients were diagnosed with ulcerative colitis (UC) and 23 (38,3%) with Crohn's disease (CD). Data from 276 control individuals were used for the determination of the prevalence of dry eye in our area. RESULTS: Ophthalmologic manifestations were diagnosed in 26 (43%) patients (14 UC, 12 CD; 12 males and 14 females). Conjunctivitis was diagnosed in 1 patient (CD), episcleritis in 2 patients (UC), and iridocyclitis in 3 (CD). Fundus examination showed 1 patient (CD) with unilateral choroiditis, 1 (UC) with retinal vasculitis, and 1 (CD) with optic neuritis. Retinal pigment epithelium disturbances (RPED) were present in 3 patients (1 CD, 2 UC) and 2 had serous retinal detachment. In total, 13/60 patients (22%) had dry eye compared with the 11% prevalence in controls. Eight patients developed glucocorticosteroid-induced cataracts, 2 of them treated surgically. CONCLUSIONS: This study demonstrated the prevalence of the spectrum of ophthalmologic manifestations in the IBD population, including some rare and silent findings that may merit consideration and early intervention.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primary10.1002/ibd.20584-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/18626979-
heal.identifier.secondaryhttp://onlinelibrary.wiley.com/store/10.1002/ibd.20584/asset/20584_ftp.pdf?v=1&t=h05ido5n&s=e19694881aa8f09ea251bf875701b070fcee965d-
heal.journalNameInflamm Bowel Disen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2009-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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