The relative value of metabolic syndrome and cardiovascular risk score estimates in premature acute coronary syndromes
Φόρτωση...
Ημερομηνία
Συγγραφείς
Kalantzi, K.
Korantzopoulos, P.
Tzimas, P.
Katsouras, C. S.
Goudevenos, J. A.
Milionis, H. J.
Τίτλος Εφημερίδας
Περιοδικό ISSN
Τίτλος τόμου
Εκδότης
Περίληψη
Τύπος
Είδος δημοσίευσης σε συνέδριο
Είδος περιοδικού
peer-reviewed
Είδος εκπαιδευτικού υλικού
Όνομα συνεδρίου
Όνομα περιοδικού
Am Heart J
Όνομα βιβλίου
Σειρά βιβλίου
Έκδοση βιβλίου
Συμπληρωματικός/δευτερεύων τίτλος
Περιγραφή
BACKGROUND: To compare the relative value of metabolic syndrome (MetS) and cardiovascular risk score estimates in patients with acute coronary syndromes (ACS) aged <45 years. PATIENTS AND METHODS: Two hundred consecutive patients (183 men, mean age 40.8 +/- 3.5 years) presented with a first-ever ACS, and 200 age-and sex-matched controls were evaluated. Metabolic syndrome diagnostic criteria, European Risk SCORE estimation function, and the Framingham Risk Score (FRS) were assessed in all participants. RESULTS: The prevalence of the MetS was significantly higher in the patients' group compared with the control group (51.5% vs 26.0%, P < .001). No subjects with a SCORE >1.0% were identified. The mean 10-year FRS for patients and controls was 13.03% +/- 7.96% and 10.02 +/- 8.10%, respectively (P < .001), whereas only 22.5% of ACS patients had a 10-year risk >20.0% compared with 14.5% of controls (P = .04). After controlling for potential confounders, MetS was associated with 1.93 (95% CI 1.13-3.28, P = .01) higher odds of having an ACS. Moreover, the odds had a positive association with the increasing cumulative number of MetS components. Crude and adjusted ORs for the FRS were 1.05 (95% CI 1.029-1.08, P = .001) and 0.98 (95% CI 0.92-1.05, P = NS), respectively. CONCLUSION: Metabolic syndrome is highly associated with ACS in subjects <45 years of age and seems to be more valuable than established cardiovascular risk calculators.
Περιγραφή
Λέξεις-κλειδιά
Adolescent, Adult, Cholesterol, LDL/blood, Coronary Disease/diagnosis/epidemiology/*etiology, Electrocardiography, Female, Follow-Up Studies, Greece/epidemiology, Humans, Male, Metabolic Syndrome X/blood/*complications/epidemiology, Middle Aged, Prevalence, Prognosis, Retrospective Studies, Risk Assessment, Risk Factors, Syndrome
Θεματική κατηγορία
Παραπομπή
Σύνδεσμος
http://www.ncbi.nlm.nih.gov/pubmed/18294493
http://ac.els-cdn.com/S0002870307008770/1-s2.0-S0002870307008770-main.pdf?_tid=553ba1a9a7c18a493f9346c21890a9a3&acdnat=1333963188_b78839d62451badcf19abfdd31a42038
http://ac.els-cdn.com/S0002870307008770/1-s2.0-S0002870307008770-main.pdf?_tid=553ba1a9a7c18a493f9346c21890a9a3&acdnat=1333963188_b78839d62451badcf19abfdd31a42038
Γλώσσα
en
Εκδίδον τμήμα/τομέας
Όνομα επιβλέποντος
Εξεταστική επιτροπή
Γενική Περιγραφή / Σχόλια
Ίδρυμα και Σχολή/Τμήμα του υποβάλλοντος
Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής