Synthesis of the novel pyrrolo[2,1-d][1,2,5]benzotriazepine, pyrrolo[2,1-e][1,3,6]benzotriazocine and pyrrolo[1,2-a]tetrazolo[1,5-d][1,4]benzodiazepine ring systems. A new route to pyrrolo[1,2a]quinoxaline via transamination of in situ generated 1-(2-aminophenyl)-2-iminomethylpyrroles
| dc.contributor.author | Korakas, D. | en |
| dc.contributor.author | Kimbaris, A. | en |
| dc.contributor.author | Varvounis, G. | en |
| dc.date.accessioned | 2015-11-24T16:49:21Z | |
| dc.date.available | 2015-11-24T16:49:21Z | |
| dc.identifier.issn | 0040-4020 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/9471 | |
| dc.rights | Default Licence | - |
| dc.subject | 2-aminomethylpyrroles | en |
| dc.subject | exchange | en |
| dc.title | Synthesis of the novel pyrrolo[2,1-d][1,2,5]benzotriazepine, pyrrolo[2,1-e][1,3,6]benzotriazocine and pyrrolo[1,2-a]tetrazolo[1,5-d][1,4]benzodiazepine ring systems. A new route to pyrrolo[1,2a]quinoxaline via transamination of in situ generated 1-(2-aminophenyl)-2-iminomethylpyrroles | en |
| heal.abstract | Selective reduction of 2-azidomethyl-1-(2-nitrophenyl)pyrrole 5 afforded 2-aminomethyl-1-(2-nitrophenyl)pyrrole 10. Pyrrolo[1,2-a]quinoxaline 15 is obtained by treating amino-ester 12 with formaldehyde. Diamine 8 reacts with either formaldehyde or benzaldehyde to give pyrrolo[1,2-a]quinoxaline 19. Compound 10 was reductively cyclised to pyrrolo[2,1-d][1,2,5]-benzotriazepine 22. Intramolecular coupling of diamine 8 with triphosgene or carbon disulfide yields pyrrolo[2,1-e][1,3,6]benzotriazocine 23 and 24, respectively. Intramolecular 1,3-dipolar cycloaddition of cyanoazide 6 gives pyrrolo[1,2-a]tetrazolo[1,5-d][1,4]benzodiazepine 25. Copyright (C) 1996 Elsevier Science Ltd | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.primary | Doi 10.1016/0040-4020(96)00597-2 | - |
| heal.identifier.secondary | <Go to ISI>://A1996VA71000017 | - |
| heal.identifier.secondary | http://ac.els-cdn.com/0040402096005972/1-s2.0-0040402096005972-main.pdf?_tid=b189e244-34ac-11e3-a092-00000aacb35d&acdnat=1381740387_b9da1d574e69bff15ae94b05cc5c38df | - |
| heal.journalName | Tetrahedron | en |
| heal.journalType | peer reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 1996 | - |
| heal.publisher | Elsevier | en |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείας | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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