O-17 and H-1-N-15 Heteronuclear Multiple-Quantum Coherence (H-1-N-15 Hmqc) Nmr of Linear Amides - Evidence of an out-of-Plane (Torsion Angle) Deformation of the Amide Bond and Pyramidicity at the Amide Nitrogen

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Gerothanassis, I. P.
Troganis, A.
Vakka, C.

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Elsevier

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peer reviewed

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Tetrahedron

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O-17 and H-1-N-15 heteronuclear multiple quantum coherence NMR studies of linear amides demonstrate the ready occurence of an out-of-plane (torsion angle) deformation of the amide bond and pyramidicity at the amide nitrogen for the sterically hindered trans-isomer of N-tert-butylformamide. Solvent accessibility, steric hindrance and, thus, torsion angle deformation is shown to be strongly solvent dependent.

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nuclear magnetic-resonance, chemical-shifts, spectroscopy, peptides, protons

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<Go to ISI>://A1995RP93400017
http://ac.els-cdn.com/004040209500551I/1-s2.0-004040209500551I-main.pdf?_tid=90f92fb0-3247-11e3-8413-00000aab0f26&acdnat=1381477051_921656a0dc8705454da7979cba6e96d1

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en

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Πανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείας

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