Allergens responsible for allergic contact dermatitis among children: a systematic review and meta-analysis
| dc.contributor.author | Bonitsis, N. | en |
| dc.contributor.author | Tatsioni, A. | en |
| dc.contributor.author | Bassioukas, K. | en |
| dc.contributor.author | Ioannidis, J. P. | en |
| dc.date.accessioned | 2015-11-24T19:37:03Z | |
| dc.date.available | 2015-11-24T19:37:03Z | |
| dc.identifier.issn | 1600-0536 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/23983 | |
| dc.rights | Default Licence | - |
| dc.subject | Allergens/*adverse effects/immunology | en |
| dc.subject | Child | en |
| dc.subject | Dermatitis, Allergic Contact/*etiology | en |
| dc.subject | Humans | en |
| dc.subject | Patch Tests | en |
| dc.title | Allergens responsible for allergic contact dermatitis among children: a systematic review and meta-analysis | en |
| heal.abstract | BACKGROUND: Multiple studies have evaluated diverse allergens in paediatric populations. Consensus is still lacking on which allergens are most commonly implicated in allergic contact dermatitis. OBJECTIVES: To evaluate the proportion of positive reactions for allergens tested in children and to identify allergens with positive reactions in at least 1% of them. METHODS: This was a systematic review of studies in PubMed (1966-2010) investigating allergens in at least 100 enrolled children. Proportions of positive reactions for each allergen were combined with random effects models across studies. RESULTS: We included 49 studies with available data on 170 allergens. Each study tested a median of two allergens. Among the 94 allergens evaluated by at least two studies, 58 had estimates of positive reactions of at least 1% by random effects calculations, and for 21 of them the 95% confidence interval ensured that the proportion of positive reactions was at least 1%. The top five allergens tested by at least two studies included nickel sulfate, ammonium persulfate, gold sodium thiosulfate, thimerosal, and toluene-2,5-diamine (p-toluenediamine). For most allergens, the proportion of positive reactions was higher in studies published after 1995 than in earlier studies (p = 0.0065). CONCLUSIONS: This meta-analysis offers guidance on which allergens are most prevalent in the paediatric population and should have priority for inclusion in standardized allergen series. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.primary | 10.1111/j.1600-0536.2010.01860.x | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/21480911 | - |
| heal.identifier.secondary | http://onlinelibrary.wiley.com/store/10.1111/j.1600-0536.2010.01860.x/asset/j.1600-0536.2010.01860.x.pdf?v=1&t=h0je0k5e&s=25fe129c1198d76cd2c11381dc2b91e1e8512c64 | - |
| heal.journalName | Contact Dermatitis | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 2011 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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