Circulating endothelin-3 levels in patients with sickle cell disease during hydroxyurea treatment
| dc.contributor.author | Makis, A. C. | en |
| dc.contributor.author | Hatzimichael, E. C. | en |
| dc.contributor.author | Kolios, G. | en |
| dc.contributor.author | Bourantas, K. L. | en |
| dc.date.accessioned | 2015-11-24T19:30:31Z | |
| dc.date.available | 2015-11-24T19:30:31Z | |
| dc.identifier.issn | 1592-8721 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/23111 | |
| dc.rights | Default Licence | - |
| dc.subject | Adult | en |
| dc.subject | Anemia, Sickle Cell/*blood/*drug therapy | en |
| dc.subject | Antisickling Agents/*therapeutic use | en |
| dc.subject | Endothelin-3/*blood | en |
| dc.subject | Female | en |
| dc.subject | Humans | en |
| dc.subject | Hydroxyurea/*therapeutic use | en |
| dc.subject | Male | en |
| dc.subject | Middle Aged | en |
| dc.title | Circulating endothelin-3 levels in patients with sickle cell disease during hydroxyurea treatment | en |
| heal.abstract | Abnormal adhesion of red blood cells to the endothelium and the production of cytokines and vasoactive substances, such as endothelin-1 contribute to the pathogenesis of microvascular occlusion in sickle cell disease (SCD), even during the steady state. Endothelin-3 (ET-3) is a vasoconstrictive agent, which has not yet been studied in SCD. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/15020278 | - |
| heal.journalName | Haematologica | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 2004 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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