Synthesis of sulfur containing dihydro-pyrrolo derivatives and their biological evaluation as antioxidants
| dc.contributor.author | Georgiou, D. | en |
| dc.contributor.author | Toutountzoglou, V. | en |
| dc.contributor.author | Muir, K. W. | en |
| dc.contributor.author | Hadjipavlou-Litina, D. | en |
| dc.contributor.author | Elemes, Y. | en |
| dc.date.accessioned | 2015-11-24T16:49:20Z | |
| dc.date.available | 2015-11-24T16:49:20Z | |
| dc.identifier.issn | 0968-0896 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/9468 | |
| dc.rights | Default Licence | - |
| dc.subject | azomethine ylides | en |
| dc.subject | imines | en |
| dc.subject | aminoacids | en |
| dc.subject | 1,3-dipolar cycloadditions | en |
| dc.subject | dihydro-pyrrole | en |
| dc.subject | sulfides | en |
| dc.subject | syn diastereoselectivity | en |
| dc.subject | x-ray | en |
| dc.subject | antioxidant activity | en |
| dc.subject | 1,3-dipolar cycloaddition reactions | en |
| dc.subject | alpha-amino-acids | en |
| dc.subject | x=y-zh systems | en |
| dc.subject | azomethine ylides | en |
| dc.subject | potential 1,3-dipoles | en |
| dc.subject | asymmetric alkylations | en |
| dc.subject | practical preparation | en |
| dc.subject | organic-synthesis | en |
| dc.subject | heterocycles | en |
| dc.subject | glycine | en |
| dc.title | Synthesis of sulfur containing dihydro-pyrrolo derivatives and their biological evaluation as antioxidants | en |
| heal.abstract | The 1,3-dipolar cycloaddition to N-phenylmaleimide of azomethine ylides, generated in situ from sulfanyl-substituted imines of glycine esters, yields 5H-dihydro-pyrrolo products with syn diastereoselectivity. The syn (major) and anti (minor) products were isolated chromatographically and fully characterized by spectroscopic methods and in two cases also by X-ray analysis. The diastereomeric cycloadducts were tested for their antioxidant activity with good results. (C) 2012 Elsevier Ltd. All rights reserved. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.primary | DOI 10.1016/j.bmc.2012.07.014 | - |
| heal.identifier.secondary | <Go to ISI>://000307828600005 | - |
| heal.identifier.secondary | http://ac.els-cdn.com/S0968089612005573/1-s2.0-S0968089612005573-main.pdf?_tid=49620a3a-356e-11e3-9586-00000aacb35d&acdnat=1381823534_f1a8faa3502f9cdd20b3466306cefe9f | - |
| heal.journalName | Bioorganic and Medicinal Chemistry | en |
| heal.journalType | peer reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 2012 | - |
| heal.publisher | Elsevier | en |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείας | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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