Prefabrication of an axial bio-synthetic flap for circumferential tracheal defect reconstruction
| dc.contributor.author | Lykoudis, E. G. | en |
| dc.contributor.author | Tsoutsos, D. A. | en |
| dc.contributor.author | Papalois, A. E. | en |
| dc.contributor.author | Frangia, K. B. | en |
| dc.contributor.author | Stamatopoulos, C. N. | en |
| dc.contributor.author | Ioannovich, J. D. | en |
| dc.date.accessioned | 2015-11-24T18:57:14Z | |
| dc.date.available | 2015-11-24T18:57:14Z | |
| dc.identifier.issn | 0007-1226 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/19144 | |
| dc.rights | Default Licence | - |
| dc.subject | Animals | en |
| dc.subject | *Bioprosthesis | en |
| dc.subject | Male | en |
| dc.subject | Polytetrafluoroethylene/therapeutic use | en |
| dc.subject | Rabbits | en |
| dc.subject | Reconstructive Surgical Procedures/*methods | en |
| dc.subject | *Surgical Flaps | en |
| dc.subject | Time Factors | en |
| dc.subject | Tissue Survival | en |
| dc.subject | Tracheal Diseases/*surgery | en |
| dc.title | Prefabrication of an axial bio-synthetic flap for circumferential tracheal defect reconstruction | en |
| heal.abstract | The aim of this study was to prefabricate an axial bio-synthetic flap for reconstruction of circumferential tracheal defects in a rabbit model. Two series of experiments were performed. In the first set of experiments axial island bio-synthetic flaps were prefabricated. These consisted of an inner island de-epithelialised fasciocutaneous flap from a rabbit's ear and an outer polytetrafluoroethylene vascular graft. The flaps were buried at the base of the rabbit's ear for periods of 1, 2 and 3 weeks (groups A, B and C, respectively), 10 flaps per group. Only one flap in group C failed to survive. Clinical and histological assessment, at the completion of each time period, showed that only the viable flaps of group C developed all the characteristics needed for a tracheal substitute. In the second set of experiments the prefabricated bio-synthetic flaps were transferred to the rabbit's neck by means of microvascular anastomoses. Ten such free flaps were buried at the rabbit's neck for 3 weeks (group D). Eight of the flaps remained viable and all the viable flaps had characteristics similar to those of group C. These results demonstrate the feasibility of creating a prefabricated axial bio-synthetic flap (island or free), over a 3-week period, possessing the characteristics needed for a tracheal substitute in a rabbit model. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.primary | 10.1054/bjps.2000.3382 | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/10927683 | - |
| heal.identifier.secondary | http://ac.els-cdn.com/S0007122600933824/1-s2.0-S0007122600933824-main.pdf?_tid=fc3dd0d1d72a853e5b8d30da3f9695dd&acdnat=1333466375_2f3023795d4d7eeb82f32bf3bc2883af | - |
| heal.journalName | Br J Plast Surg | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 2000 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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