Influence of nutritional factors on bone collagen fibrils in ovariectomized rats

dc.contributor.authorTzaphlidou, M.en
dc.contributor.authorKafantari, H.en
dc.date.accessioned2015-11-24T19:10:00Z
dc.date.available2015-11-24T19:10:00Z
dc.identifier.issn8756-3282-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/20777
dc.rightsDefault Licence-
dc.subject*Animal Nutritional Physiological Phenomenaen
dc.subjectAnimalsen
dc.subjectBone and Bones/*metabolism/ultrastructureen
dc.subjectCollagen/*metabolismen
dc.subjectFemaleen
dc.subjectMicroscopy, Electronen
dc.subjectOvariectomyen
dc.subjectRatsen
dc.subjectRats, Wistaren
dc.subjectVitamin D/administration & dosageen
dc.titleInfluence of nutritional factors on bone collagen fibrils in ovariectomized ratsen
heal.abstractThe influence of both vitamin D(3) and Ca:P ratio on bone collagen fibrils was investigated in ovariectomized rats. Six weeks after ovariectomy the rats were maintained for 80 days with diets containing vitamin D(3) and calcium supplementation. Age-matched ovariectomized animals were fed a normal diet. When vitamin D(3) was increased in the diet, although no effect in fibril organization was observed in relation to that from ovariectomized rats with the normal diet, a highly significant effect in fibril diameter was detected. When the calcium:phosphorus (Ca:P) ratio was increased from 1:1 to 2:1 (without vitamin D(3) supplementation) both structural fiber parameters were significantly affected. The results were closer to normal (i.e., collagen fibrils from animals without ovariectomy) when vitamin D(3) and Ca:P ratios were combined.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/11062349-
heal.identifier.secondaryhttp://ac.els-cdn.com/S8756328200003823/1-s2.0-S8756328200003823-main.pdf?_tid=5352407113f810b51bc76fd71bfb9c7f&acdnat=1333106294_51c10dce52fe579450d0d5ef4c2b5632-
heal.journalNameBoneen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2000-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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