Randomised controlled trials in orthopaedic surgery and traumatology: overview of parameters and pitfalls

dc.contributor.authorSoucacos, P. N.en
dc.contributor.authorJohnson, E. O.en
dc.contributor.authorBabis, G.en
dc.date.accessioned2015-11-24T18:55:06Z
dc.date.available2015-11-24T18:55:06Z
dc.identifier.issn0020-1383-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/18808
dc.rightsDefault Licence-
dc.subjectEvidence-Based Medicine/methodsen
dc.subjectHumansen
dc.subject*Orthopedic Proceduresen
dc.subjectOutcome Assessment (Health Care)/methodsen
dc.subjectRandomized Controlled Trials as Topic/*methodsen
dc.subjectResearch Designen
dc.subjectStatistics as Topicen
dc.subjectWounds and Injuries/*surgeryen
dc.titleRandomised controlled trials in orthopaedic surgery and traumatology: overview of parameters and pitfallsen
heal.abstractThere is a growing consensus that randomised controlled clinical trial (RCT) provide a secure basis for determining treatment effects. Prospective randomised clinical trials can be a powerful tool in medical science and evidence-based medicine. A well-defined study hypothesis, with a prospectively applied study design, blinded and randomised treatment allocation and assessment, with appropriate control groups can provide strong evidence in support of treatment decisions. However, the recent reviews of the medical literature indicate that the study design itself does not ensure the quality of science or useful and valid scientific data. Thus, regardless of the study design or level of evidence, it remains imperative for the physician and surgeon to critically evaluate a scientific report. Moreover, as randomisation, concealment of treatment allocation and blinding are difficult issues to resolve in orthopaedic surgery, future trials should focus on detailed and correct reporting of outcome measures.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primary10.1016/j.injury.2008.02.011-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/18533154-
heal.identifier.secondaryhttp://ac.els-cdn.com/S0020138308001071/1-s2.0-S0020138308001071-main.pdf?_tid=52e4bf3a2c3cb6b473ccb5ff5086af82&acdnat=1334047843_29ff69014fd66c439529a50a1718db1c-
heal.journalNameInjuryen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2008-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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