Correlation of prostate specific antigen immunoactivity (IR-PSA) to other prognostic factors in female breast cancer
dc.contributor.author | Griniatsos, J. | en |
dc.contributor.author | Diamantis, E. | en |
dc.contributor.author | Gioti, J. | en |
dc.contributor.author | Karyda, I. | en |
dc.contributor.author | Vassilopoulos, P. P. | en |
dc.contributor.author | Agnanti, N. | en |
dc.date.accessioned | 2015-11-24T19:26:42Z | |
dc.date.available | 2015-11-24T19:26:42Z | |
dc.identifier.issn | 0250-7005 | - |
dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/22752 | |
dc.rights | Default Licence | - |
dc.subject | Adult | en |
dc.subject | Aged | en |
dc.subject | Breast Neoplasms/*metabolism/pathology | en |
dc.subject | Female | en |
dc.subject | Fluorometry | en |
dc.subject | Humans | en |
dc.subject | Middle Aged | en |
dc.subject | Neoplasm Recurrence, Local | en |
dc.subject | Prognosis | en |
dc.subject | Prostate-Specific Antigen/*metabolism | en |
dc.subject | Retrospective Studies | en |
dc.subject | Tumor Suppressor Protein p53/metabolism | en |
dc.title | Correlation of prostate specific antigen immunoactivity (IR-PSA) to other prognostic factors in female breast cancer | en |
heal.abstract | Recently, using an ultrasensitive time-resolved immuno-fluorometric assay, PSA immunoreactivity (IR-PSA) was found in breast tumor cytosols. We retrospectively studied 219 breast cancer patients, measuring IR-PSA in the tumor cytosols, and classified the breast cancers as either PSA positive or PSA negative based on an IR-PSA cut off level of 1 pg/mg. Multivariated analysis showed that IR-PSA is an independent favourable prognostic indicator for postmenopausal, node positive breast cancer patients. Additionally, IR-PSA correlates with reduced risk of relapse in ER+ve tumors and is negatively correlated with mutated p53, which increases the risk of relapse. | en |
heal.access | campus | - |
heal.fullTextAvailability | TRUE | - |
heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/9584052 | - |
heal.journalName | Anticancer Res | en |
heal.journalType | peer-reviewed | - |
heal.language | en | - |
heal.publicationDate | 1998 | - |
heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
heal.type | journalArticle | - |
heal.type.el | Άρθρο Περιοδικού | el |
heal.type.en | Journal article | en |
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