Correlation of prostate specific antigen immunoactivity (IR-PSA) to other prognostic factors in female breast cancer

dc.contributor.authorGriniatsos, J.en
dc.contributor.authorDiamantis, E.en
dc.contributor.authorGioti, J.en
dc.contributor.authorKaryda, I.en
dc.contributor.authorVassilopoulos, P. P.en
dc.contributor.authorAgnanti, N.en
dc.date.accessioned2015-11-24T19:26:42Z
dc.date.available2015-11-24T19:26:42Z
dc.identifier.issn0250-7005-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/22752
dc.rightsDefault Licence-
dc.subjectAdulten
dc.subjectAgeden
dc.subjectBreast Neoplasms/*metabolism/pathologyen
dc.subjectFemaleen
dc.subjectFluorometryen
dc.subjectHumansen
dc.subjectMiddle Ageden
dc.subjectNeoplasm Recurrence, Localen
dc.subjectPrognosisen
dc.subjectProstate-Specific Antigen/*metabolismen
dc.subjectRetrospective Studiesen
dc.subjectTumor Suppressor Protein p53/metabolismen
dc.titleCorrelation of prostate specific antigen immunoactivity (IR-PSA) to other prognostic factors in female breast canceren
heal.abstractRecently, using an ultrasensitive time-resolved immuno-fluorometric assay, PSA immunoreactivity (IR-PSA) was found in breast tumor cytosols. We retrospectively studied 219 breast cancer patients, measuring IR-PSA in the tumor cytosols, and classified the breast cancers as either PSA positive or PSA negative based on an IR-PSA cut off level of 1 pg/mg. Multivariated analysis showed that IR-PSA is an independent favourable prognostic indicator for postmenopausal, node positive breast cancer patients. Additionally, IR-PSA correlates with reduced risk of relapse in ER+ve tumors and is negatively correlated with mutated p53, which increases the risk of relapse.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/9584052-
heal.journalNameAnticancer Resen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate1998-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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