Recombinant human erythropoietin treatment of postpartum anemia. Preliminary results
Φόρτωση...
Ημερομηνία
Τίτλος Εφημερίδας
Περιοδικό ISSN
Τίτλος τόμου
Εκδότης
Περίληψη
Τύπος
Είδος δημοσίευσης σε συνέδριο
Είδος περιοδικού
peer-reviewed
Είδος εκπαιδευτικού υλικού
Όνομα συνεδρίου
Όνομα περιοδικού
Eur J Obstet Gynecol Reprod Biol
Όνομα βιβλίου
Σειρά βιβλίου
Έκδοση βιβλίου
Συμπληρωματικός/δευτερεύων τίτλος
Περιγραφή
OBJECTIVES: The aim of this study was to investigate the efficacy of recombinant human erythropoietin (rHuEpo) in postpartum anemia. STUDY DESIGN: At the University Hospital of Ioannina, rHuEpo was administrated subcutaneously to twenty anemic women (hemoglobin [Hb]<10 g/dl), for 15 days following delivery; all were given iron and folic acid per os. Twenty other women (the control group) with postpartum anemia (Hb<10 g/dl), received only iron and folic acid. The Mann-Whitney U-test was used for the comparison of hematological indices between the two groups, on days 1, 3, 5, 10, 15 and 40 postdelivery. RESULTS: On day 3, reticulocyte counts were significantly higher in the women who received rHuEpo, as compared to the controls (P<0.05). The mean Hb value increased to >2 g/dl in the group undergoing rHuEpo therapy as compared to 0.7 g/dl in the control group on day 5 (P<0.05). Furthermore, two women in the control group required blood transfusions, while no transfusions were required by the rHuEpo group. CONCLUSIONS: rHuEpo administration is useful for a more rapid amelioration of hematological indices in women with postpartum anemia. Further, the dose given in this study was not associated with significant side-effects.
Περιγραφή
Λέξεις-κλειδιά
Adolescent, Adult, Anemia/blood/*drug therapy, Blood Transfusion, Erythropoietin/*therapeutic use, Female, Folic Acid/therapeutic use, Hemoglobins/analysis, Humans, Iron/therapeutic use, Length of Stay, Prospective Studies, Puerperal Disorders/*drug therapy, Recombinant Proteins, Reticulocyte Count
Θεματική κατηγορία
Παραπομπή
Σύνδεσμος
http://www.ncbi.nlm.nih.gov/pubmed/9846709
http://ac.els-cdn.com/S0301211598001584/1-s2.0-S0301211598001584-main.pdf?_tid=08a33865fdd93f38f030acc7546f0a96&acdnat=1337251416_3932dbb891def2f8009c5c1b7e9ef4dd
http://ac.els-cdn.com/S0301211598001584/1-s2.0-S0301211598001584-main.pdf?_tid=08a33865fdd93f38f030acc7546f0a96&acdnat=1337251416_3932dbb891def2f8009c5c1b7e9ef4dd
Γλώσσα
en
Εκδίδον τμήμα/τομέας
Όνομα επιβλέποντος
Εξεταστική επιτροπή
Γενική Περιγραφή / Σχόλια
Ίδρυμα και Σχολή/Τμήμα του υποβάλλοντος
Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής