Recombinant human erythropoietin treatment of postpartum anemia. Preliminary results
| dc.contributor.author | Makrydimas, G. | en |
| dc.contributor.author | Lolis, D. | en |
| dc.contributor.author | Lialios, G. | en |
| dc.contributor.author | Tsiara, S. | en |
| dc.contributor.author | Georgiou, I. | en |
| dc.contributor.author | Bourantas, K. L. | en |
| dc.date.accessioned | 2015-11-24T18:54:51Z | |
| dc.date.available | 2015-11-24T18:54:51Z | |
| dc.identifier.issn | 0301-2115 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/18759 | |
| dc.rights | Default Licence | - |
| dc.subject | Adolescent | en |
| dc.subject | Adult | en |
| dc.subject | Anemia/blood/*drug therapy | en |
| dc.subject | Blood Transfusion | en |
| dc.subject | Erythropoietin/*therapeutic use | en |
| dc.subject | Female | en |
| dc.subject | Folic Acid/therapeutic use | en |
| dc.subject | Hemoglobins/analysis | en |
| dc.subject | Humans | en |
| dc.subject | Iron/therapeutic use | en |
| dc.subject | Length of Stay | en |
| dc.subject | Prospective Studies | en |
| dc.subject | Puerperal Disorders/*drug therapy | en |
| dc.subject | Recombinant Proteins | en |
| dc.subject | Reticulocyte Count | en |
| dc.title | Recombinant human erythropoietin treatment of postpartum anemia. Preliminary results | en |
| heal.abstract | OBJECTIVES: The aim of this study was to investigate the efficacy of recombinant human erythropoietin (rHuEpo) in postpartum anemia. STUDY DESIGN: At the University Hospital of Ioannina, rHuEpo was administrated subcutaneously to twenty anemic women (hemoglobin [Hb]<10 g/dl), for 15 days following delivery; all were given iron and folic acid per os. Twenty other women (the control group) with postpartum anemia (Hb<10 g/dl), received only iron and folic acid. The Mann-Whitney U-test was used for the comparison of hematological indices between the two groups, on days 1, 3, 5, 10, 15 and 40 postdelivery. RESULTS: On day 3, reticulocyte counts were significantly higher in the women who received rHuEpo, as compared to the controls (P<0.05). The mean Hb value increased to >2 g/dl in the group undergoing rHuEpo therapy as compared to 0.7 g/dl in the control group on day 5 (P<0.05). Furthermore, two women in the control group required blood transfusions, while no transfusions were required by the rHuEpo group. CONCLUSIONS: rHuEpo administration is useful for a more rapid amelioration of hematological indices in women with postpartum anemia. Further, the dose given in this study was not associated with significant side-effects. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/9846709 | - |
| heal.identifier.secondary | http://ac.els-cdn.com/S0301211598001584/1-s2.0-S0301211598001584-main.pdf?_tid=08a33865fdd93f38f030acc7546f0a96&acdnat=1337251416_3932dbb891def2f8009c5c1b7e9ef4dd | - |
| heal.journalName | Eur J Obstet Gynecol Reprod Biol | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 1998 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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