Epstein-Barr virus-associated high-grade anaplastic plasmacytoma in a renal transplant patient
| dc.contributor.author | Papadaki, H. A. | en |
| dc.contributor.author | Stefanaki, K. | en |
| dc.contributor.author | Kanavaros, P. | en |
| dc.contributor.author | Katonis, P. | en |
| dc.contributor.author | Papastathi, H. | en |
| dc.contributor.author | Valatas, W. | en |
| dc.contributor.author | Stylianoy, K. | en |
| dc.contributor.author | Eliopoulos, G. D. | en |
| dc.date.accessioned | 2015-11-24T19:18:42Z | |
| dc.date.available | 2015-11-24T19:18:42Z | |
| dc.identifier.issn | 1042-8194 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/21890 | |
| dc.rights | Default Licence | - |
| dc.subject | Herpesvirus 4, Human/*isolation & purification | en |
| dc.subject | Humans | en |
| dc.subject | In Situ Hybridization | en |
| dc.subject | Kidney Transplantation/*adverse effects | en |
| dc.subject | Lymphoproliferative Disorders/*etiology/pathology | en |
| dc.subject | Male | en |
| dc.subject | Middle Aged | en |
| dc.subject | Mouth Neoplasms/etiology/pathology/virology | en |
| dc.subject | Multiple Myeloma/*etiology/pathology/virology | en |
| dc.subject | Scalp | en |
| dc.subject | Skin Neoplasms/etiology/pathology/virology | en |
| dc.title | Epstein-Barr virus-associated high-grade anaplastic plasmacytoma in a renal transplant patient | en |
| heal.abstract | Allograft transplant patients have an increased risk of developing polyclonal or monoclonal lymphoproliferative disorders, but high-grade anaplastic plasmacytomas are extremely rare in these patients. We present a renal transplant patient who developed multiple extramedullary high-grade anaplastic plasmacytomas in the oral cavity, the left maxillary antrum, the scalp, the thigh and the upper abdominal wall with no evidence of diffuse bone marrow infiltration. Epstein-Barr virus (EBV) mRNA transcripts were detected within the myeloma cells by in situ hybridization using EBER1-2 probes. Following discontinuation of immunosuppression applied, the patient was treated with a cyclophosphamide-prednisone regimen followed by local irradiation, and a complete remission was achieved within four weeks. We concluded that EBV-associated high-grade anaplastic plasmacytomas constitute one more type of post-transplant lymphoproliferative disorder, and that despite their characterization as highly malignant neoplasms, their clinical behavior is not always aggressive. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.primary | 10.3109/10428190009148863 | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/10674914 | - |
| heal.journalName | Leuk Lymphoma | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 2000 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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